Concepedia

Profile-to-sequence Alignment

Profile-To-Sequence Alignment is a computational method in bioinformatics that aligns a biological sequence to a profile hidden Markov model, leveraging the model's position-specific scoring framework to capture conserved patterns and insertions or deletions characteristic of homologous families.

85

Publications

54.4K

Citations

217

Authors

115

Institutions

Publications per year

2017–2026

6

Parents

Publications

85

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

Julie Thompson · Nucleic Acids Research · 1997 · 39.2K citations · Full text

, , +13

Infernal 1.1: 100-fold faster RNA homology searches

Eric P. Nawrocki, Sean R. Eddy · Bioinformatics · 2013 · 3.9K citations · Full text

, , +16

Multiple Sequence Alignment Using ClustalW and ClustalX

Julie Thompson, Toby J. Gibson, Desmond G. Higgins · Current Protocols in Bioinformatics · 2002 · 3.1K citations

, , +14

Protein–ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment

Jianyi Yang, Ambrish Roy, Yang Zhang · Bioinformatics · 2013 · 1.1K citations · Full text

, , +13

A novel hybrid gene prediction method employing protein multiple sequence alignments

Oliver Keller, Martin Kollmar, Mario Stanke et al. · Bioinformatics · 2011 · 627 citations · Full text

, , +13

1–5 of 85

Authors

217

  1. NV
    Nick V. Grishin

    The University of Texas Southwestern Medical Center, United States

    4 publications · 655 citations

    4

    h-index

  2. JT
    Julie Thompson

    Centre National de la Recherche Scientifique, France

    4 publications · 42.8K citations

    4

    h-index

  3. RI
    Ruslan I. Sadreyev

    Massachusetts General Hospital, United States

    3 publications · 307 citations

    3

    h-index

  4. BH
    Barry Honig

    Columbia University, United States

    3 publications · 478 citations

    3

    h-index

  5. TJ
    Toby J. Gibson

    European Molecular Biology Laboratory, Germany

    3 publications · 3.5K citations

    3

    h-index

1–5 of 217

Institutions

115

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    26 publications

    5.8K citations

  2. European Molecular Biology Laboratory

    Heidelberg, Germany

    5 h-index

    5 publications

    3.8K citations

  3. European Molecular Biology Laboratory

    Hamburg, Germany

    5 h-index

    8 publications

    1.4K citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    13 publications

    536 citations

  5. The University of Texas Southwestern Medical Center

    Dallas, United States

    4 h-index

    9 publications

    1.5K citations

  6. Columbia University

    New York, United States

    4 h-index

    20 publications

    4.5K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    17 publications

    438 citations

  8. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    4 h-index

    14 publications

    316 citations

1–8 of 115

Venues

  1. Bioinformatics

    24 publications · 7.4K citations

    19

    h-index

  2. Nucleic Acids Research

    13 publications · 40.8K citations

    12

    h-index

  3. BMC Bioinformatics

    9 publications · 291 citations

    9

    h-index

  4. Protein Science

    PS · 3 publications · 377 citations

    3

    h-index

  5. Journal of Molecular Biology

    JMB · 3 publications · 275 citations

    3

    h-index

1–5