Concepedia

Process Impurities Removal

Process Impurities Removal is a methodological procedure within ion-exchange chromatography that selectively separates and eliminates contaminant molecules originating from upstream bioprocessing steps, distinguishing itself from related purification techniques by its specificity for non-product entities such as host cell proteins, nucleic acids, and endotoxins based on differential ionic interactions with the chromatographic matrix.

60

Publications

1.8K

Citations

321

Authors

86

Institutions

Publications per year

2017–2026

23

Parents

Publications

60

REMOVAL OF THE IMPURITIES, NUCLEIC ACID AND POLYSACCHARIDE, FROM TUBERCULIN PROTEIN

Florence B. Seibert · Journal of Biological Chemistry · 1940 · 157 citations · Full text

, , +15

Multiplex secretome engineering enhances recombinant protein production and purity

Stefan Kol, Daniel Ley, Tune Wulff et al. · Nature Communications · 2020 · 127 citations · Full text

, , +17

Development of robust antibody purification by optimizing protein‐A chromatography in combination with precipitation methodologies

Srinivas Chollangi, Ray Parker, Nripen Singh et al. · Biotechnology and Bioengineering · 2015 · 94 citations

, , +17

Impurities in biogas: Analytical strategies, occurrence, effects and removal technologies

Idalina Bragança, Francisco Sánchez-Soberón, Gabriel F. Pantuzza et al. · Biomass and Bioenergy · 2020 · 77 citations

, , +14

Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes

György Székely, Marco Gil, Börje Sellergren et al. · Green Chemistry · 2012 · 60 citations

, , +17

1–5 of 60

Authors

321

  1. AB
    Anke Bockreis

    Universität Innsbruck, Austria

    3 publications · 106 citations

    3

    h-index

  2. WM
    Wolfgang Müller

    Royal Holloway University of London, United Kingdom

    3 publications · 106 citations

    3

    h-index

  3. FG
    Frédéric Gerke

    Universität Innsbruck, Austria

    2 publications · 74 citations

    2

    h-index

  4. SR
    Sabine Robra

    Universität Innsbruck, Austria

    2 publications · 81 citations

    2

    h-index

  5. TW
    Tune Wulff

    Technical University of Denmark, Denmark

    2 publications · 143 citations

    2

    h-index

1–5 of 321

Institutions

86

  1. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    4 h-index

    15 publications

    327 citations

  2. Bristol-Myers Squibb (United States)

    New York, United States

    3 h-index

    30 publications

    824 citations

  3. Universität Innsbruck

    Innsbruck, Austria

    3 h-index

    16 publications

    579 citations

  4. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    25 publications

    2K citations

  5. Central South University

    Changsha, China

    2 h-index

    2 publications

    72 citations

  6. Janssen (Belgium)

    Beerse, Belgium

    2 h-index

    1 publications

    18 citations

  7. Novo Nordisk (United States)

    Seattle, United States

    2 h-index

    8 publications

    683 citations

  8. Bristol-Myers Squibb (Germany)

    Munich, Germany

    2 h-index

    6 publications

    564 citations

1–8 of 86

Venues

  1. Organic Process Research & Development

    15 publications · 258 citations

    11

    h-index

  2. Waste Management

    3 publications · 106 citations

    3

    h-index

  3. 3

    h-index

  4. Journal of Separation Science

    2 publications · 47 citations

    2

    h-index

  5. Biotechnology and Bioengineering

    2 publications · 114 citations

    2

    h-index

1–5