Concepedia

Primitive Endoderm Specification

Primitive Endoderm Specification is a developmental biology process that refers to the commitment of pluripotent epiblast cells to the primitive endoderm lineage during early mammalian embryogenesis, distinguished by the activation of specific transcriptional regulators such as GATA6 and NANOG downregulation.

146

Publications

15.7K

Citations

704

Authors

279

Institutions

Publications per year

2017–2026

38

Parents

Publications

146

Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway

Claire Chazaud, Yojiro Yamanaka, Tony Pawson et al. · Developmental Cell · 2006 · 920 citations · Full text

, , +17

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

Yojiro Yamanaka, Fredrik Lanner, Janet Rossant · Development · 2010 · 599 citations

, , +17

Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

Paul Q. Thomas, Rosa Beddington · Current Biology · 1996 · 554 citations · Full text

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<i>Hex</i>: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors

Paul Q. Thomas, Angus M. Brown, R. S. P. Beddington · Development · 1998 · 530 citations

, , +17

Postimplantation expression patterns indicate a role for the mouse <i>forkhead</i>/HNF-3 α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm

A. Paula Monaghan, Klaus H. Kaestner, Evelyn Grau et al. · Development · 1993 · 503 citations

, , +14

1–5 of 146

Authors

704

  1. AH
    Anna‐Katerina Hadjantonakis

    Kettering University, United States

    8 publications · 1.4K citations

    8

    h-index

  2. CC
    Claire Chazaud

    Inserm, France

    7 publications · 1.6K citations

    7

    h-index

  3. CC
    Craig C. Malbon

    Stony Brook University, United States

    7 publications · 597 citations

    7

    h-index

  4. JA
    Jérôme Artus

    Kettering University, United States

    6 publications · 779 citations

    6

    h-index

  5. JM
    Joshua M. Brickman

    University of Copenhagen, Denmark

    5 publications · 413 citations

    5

    h-index

1–5 of 704

Institutions

279

  1. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    47 publications

    4K citations

  2. Inserm

    Paris, France

    10 h-index

    28 publications

    5K citations

  3. Stony Brook University

    Stony Brook, United States

    8 h-index

    21 publications

    1.5K citations

  4. Kettering University

    Flint, United States

    8 h-index

    20 publications

    3.7K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    23 publications

    3.9K citations

  6. University of Copenhagen

    Copenhagen, Denmark

    6 h-index

    16 publications

    1.5K citations

  7. Harvard University

    Cambridge, United States

    6 h-index

    13 publications

    3.8K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    13 publications

    3.7K citations

1–8 of 279

Venues

  1. Development

    27 publications · 5.7K citations

    26

    h-index

  2. Developmental Biology

    15 publications · 1.6K citations

    15

    h-index

  3. Journal of Biological Chemistry

    JBC · 6 publications · 248 citations

    6

    h-index

  4. Journal of Cell Science

    5 publications · 239 citations

    5

    h-index

  5. Developmental Cell

    5 publications · 1.7K citations

    5

    h-index

1–5