Concepedia

Primary Nonresponse

Primary Nonresponse is a treatment outcome in Crohn disease pharmacotherapy characterized by the failure to achieve initial therapeutic benefit following the initiation of a biologic or pharmacologic agent, distinguishing it from secondary nonresponse or loss of response after prior efficacy.

55

Publications

4.6K

Citations

477

Authors

250

Institutions

Publications per year

2017–2026

27

Variants

Primary Non-response

Parents

Publications

55

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

Brian G. Feagan, William J. Sandborn, Christopher Gasink et al. · New England Journal of Medicine · 2016 · 1.8K citations · Full text

, , +17

Role for Therapeutic Drug Monitoring During Induction Therapy with TNF Antagonists in IBD

Konstantinos Papamichael, Ann Gils, Paul Rutgeerts et al. · Inflammatory Bowel Diseases · 2014 · 243 citations · Full text

, , +17

Evaluating interventions with differential attrition: The importance of nonresponse mechanisms and use of follow-up data.

J. A. Graham, Stewart I. Donaldson · Journal of Applied Psychology · 1993 · 202 citations

, , +12

The CHOICE trial: adalimumab demonstrates safety, fistula healing, improved quality of life and increased work productivity in patients with Crohn’s disease who failed prior infliximab therapy

Simon Lichtiger, DG Binion, Douglas C. Wolf et al. · Alimentary Pharmacology & Therapeutics · 2010 · 186 citations

, , +17

Vedolizumab as Induction and Maintenance Therapy for Crohnʼs Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy

Bruce E. Sands, William J. Sandborn, Gert Van Assche et al. · Inflammatory Bowel Diseases · 2016 · 184 citations

, , +15

1–5 of 55

Authors

477

  1. WJ
    William J. Sandborn

    University of California San Diego, United States

    3 publications · 2.2K citations

    3

    h-index

  2. SR
    Stephan R. Targan

    Cedars-Sinai Medical Center, United States

    3 publications · 2K citations

    3

    h-index

  3. SV
    Séverine Vermeire

    KU Leuven, Belgium

    3 publications · 2.1K citations

    3

    h-index

  4. AG
    Ann Gils

    KU Leuven, Belgium

    2 publications · 315 citations

    2

    h-index

  5. JA
    J. A. Graham

    Carnegie Institution for Science, United States

    2 publications · 215 citations

    2

    h-index

1–5 of 477

Institutions

250

  1. University of California San Diego

    San Diego, United States

    4 h-index

    6 publications

    2.7K citations

  2. Cedars-Sinai Medical Center

    Los Angeles, United States

    4 h-index

    25 publications

    3.5K citations

  3. Icahn School of Medicine at Mount Sinai

    New York, United States

    3 h-index

    4 publications

    3.8K citations

  4. Asan Medical Center

    Seoul, South Korea

    3 h-index

    15 publications

    378 citations

  5. University of Toronto

    Toronto, Canada

    3 h-index

    11 publications

    235 citations

  6. University of Ulsan

    Ulsan, South Korea

    3 h-index

    15 publications

    378 citations

  7. KU Leuven

    Leuven, Belgium

    3 h-index

    11 publications

    1.2K citations

  8. Western University

    London, Canada

    3 h-index

    32 publications

    49.8K citations

1–8 of 250

Venues

  1. Inflammatory Bowel Diseases

    10 publications · 856 citations

    10

    h-index

  2. Journal of Crohn s and Colitis

    JCC · 4 publications · 144 citations

    4

    h-index

  3. Alimentary Pharmacology & Therapeutics

    4 publications · 418 citations

    4

    h-index

  4. Journal of Applied Psychology

    2 publications · 215 citations

    2

    h-index

  5. Journal of Pediatric Gastroenterology and Nutrition

    JPGN · 2 publications · 93 citations

    2

    h-index

1–5