Concepedia

Primary Bile Acids

Primary Bile Acids is a class of bile acids synthesized de novo from cholesterol in the hepatocytes of the liver, distinguished from secondary bile acids by their unaltered structure following intestinal microbial modification.

710

Publications

40.9K

Citations

3.8K

Authors

1.1K

Institutions

Publications per year

2017–2026

229

Parents

Publications

710

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

S Andersson, Daphne L. Davis, Helena Dahlbäck et al. · Journal of Biological Chemistry · 1989 · 1.2K citations · Full text

, , +17

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

Na Jiao, Susan S. Baker, Adrián Chapa‐Rodríguez et al. · Gut · 2017 · 733 citations

, , +17

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

Jonathan R. Swann, Elizabeth J. Want, Florian Geier et al. · Proceedings of the National Academy of Sciences · 2010 · 726 citations

, , +14

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Siamak MahmoudianDehkordi, Matthias Arnold, Kwangsik Nho et al. · Alzheimer s & Dementia · 2018 · 694 citations · Full text

, , +17

Dissolution of Cholesterol Gallstones by Chenodeoxycholic Acid

R. G. Danzinger, Alan F. Hofmann, Leslie J. Schoenfield et al. · New England Journal of Medicine · 1972 · 657 citations

, , +17

1–5 of 710

Authors

3.8K

  1. KD
    Kenneth D.R. Setchell

    Cincinnati Children's Hospital Medical Center, United States

    14 publications · 780 citations

    14

    h-index

  2. AF
    Alan F. Hofmann

    University of California San Diego, United States

    14 publications · 1.2K citations

    13

    h-index

  3. LR
    Lee R. Hagey

    University of California San Diego, United States

    13 publications · 497 citations

    12

    h-index

  4. HA
    Hani Al‐Salami

    Curtin University, Australia

    11 publications · 279 citations

    11

    h-index

  5. JE
    James E. Heubi

    Cincinnati Children's Hospital Medical Center, United States

    10 publications · 597 citations

    10

    h-index

1–5 of 3.8K

Institutions

1.1K

  1. Karolinska Institutet

    Stockholm, Sweden

    18 h-index

    74 publications

    5.6K citations

  2. Imperial College London

    London, United Kingdom

    17 h-index

    72 publications

    9.6K citations

  3. University of California San Diego

    San Diego, United States

    14 h-index

    47 publications

    2.7K citations

  4. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    14 h-index

    36 publications

    2.7K citations

  5. Guy's Hospital

    London, United Kingdom

    14 h-index

    26 publications

    1.3K citations

  6. Inserm

    Paris, France

    13 h-index

    62 publications

    6.5K citations

  7. Curtin University

    Perth, Australia

    12 h-index

    70 publications

    1.8K citations

  8. Karolinska University Hospital

    Stockholm, Sweden

    12 h-index

    32 publications

    1.3K citations

1–8 of 1.1K

Venues

  1. Journal of Lipid Research

    JLR · 44 publications · 2.8K citations

    27

    h-index

  2. Hepatology

    29 publications · 2.2K citations

    24

    h-index

  3. PubMed

    Repository · 34 publications · 1.4K citations

    22

    h-index

  4. Gut

    15 publications · 1.7K citations

    15

    h-index

  5. Scientific Reports

    13 publications · 866 citations

    13

    h-index

1–5