Concepedia

Presequence Protease Processing

Presequence Protease Processing is a mitochondrial enzymatic mechanism that belongs to the class of post-translational protein modification events, specifically characterized by the cleavage of N-terminal targeting presequences from nuclear-encoded proteins upon their import into the mitochondrial matrix, thereby enabling proper protein folding, assembly, and functional activation within the organelle.

23

Publications

1.4K

Citations

109

Authors

47

Institutions

Publications per year

2017–2026

7

Parents

Publications

23

Degradation of the Amyloid β-Protein by the Novel Mitochondrial Peptidasome, PreP

Annelie Falkevall, Nyosha Alikhani, Shashi Bhushan et al. · Journal of Biological Chemistry · 2006 · 201 citations · Full text

, , +13

Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization

F.‐Nora Vögtle, Claudia Prinz, Josef Kellermann et al. · Molecular Biology of the Cell · 2011 · 137 citations

, , +16

Isolation and Identification of a Novel Mitochondrial Metalloprotease (PreP) That Degrades Targeting Presequences in Plants

Anne-lie Ståhl, Per Moberg, Oleg Panfilov et al. · Journal of Biological Chemistry · 2002 · 133 citations · Full text

, , +15

Comparative Analysis of Mitochondrial N-Termini from Mouse, Human, and Yeast

Sarah E. Calvo, Olivier Julien, Karl R. Clauser et al. · Molecular & Cellular Proteomics · 2017 · 105 citations · Full text

, , +15

The closed structure of presequence protease PreP forms a unique 10 000 Å3 chamber for proteolysis

Kenneth A. Johnson, Shashi Bhushan, Anne-lie Ståhl et al. · The EMBO Journal · 2006 · 103 citations

, , +14

1–5 of 23

Authors

109

  1. EG
    Elżbieta Glaser

    Stockholm University, Sweden

    8 publications · 540 citations

    8

    h-index

  2. FV
    F.‐Nora Vögtle

    University of Freiburg, Germany

    5 publications · 283 citations

    5

    h-index

  3. PF
    Pedro Filipe Teixeira

    Stockholm University, Sweden

    4 publications · 80 citations

    4

    h-index

  4. AA
    Aslı Aras Taşkin

    University of Freiburg, Germany

    3 publications · 89 citations

    3

    h-index

  5. AS
    Anne-lie Ståhl

    Lund University, Sweden

    3 publications · 259 citations

    3

    h-index

1–5 of 109

Institutions

47

  1. Stockholm University

    Stockholm, Sweden

    8 h-index

    29 publications

    2.5K citations

  2. University of Freiburg

    Freiburg im Breisgau, Germany

    5 h-index

    28 publications

    1.6K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    4 h-index

    12 publications

    1.3K citations

  4. Science for Life Laboratory

    Stockholm, Sweden

    2 h-index

    4 publications

    98 citations

  5. Universitätsmedizin Göttingen

    Göttingen, Germany

    2 h-index

    10 publications

    615 citations

  6. National Heart Lung and Blood Institute

    Bethesda, United States

    2 h-index

    3 publications

    53 citations

  7. Max Planck Institute for Biology of Ageing

    Cologne, Germany

    2 h-index

    3 publications

    212 citations

  8. University of Göttingen

    Göttingen, Germany

    2 h-index

    6 publications

    355 citations

1–8 of 47

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 454 citations

    4

    h-index

  2. Molecular Biology of the Cell

    MBC · 3 publications · 183 citations

    3

    h-index

  3. The EMBO Journal

    2 publications · 185 citations

    2

    h-index

  4. Free Radical Biology and Medicine

    2 publications · 39 citations

    2

    h-index

  5. Journal of Proteome Research

    JPR · 1 publications · 32 citations

    1

    h-index

1–5