Concepedia

Preprohormone Structure

Preprohormone Structure is a molecular precursor construct in peptide hormone biosynthesis that consists of a nascent polypeptide chain containing an amino-terminal signal peptide, a cleavable prohormone region, and the mature hormone sequence, distinguished by its role as the initially translated, inactive form requiring proteolytic processing to yield biologically active hormone and intermediate fragments.

39

Publications

2.3K

Citations

148

Authors

60

Institutions

Publications per year

2017–2026

0

Parents

Publications

39

Structural and Physiologic Characterization of the Mid-region Secretory Species of Parathyroid Hormone-related Protein

Terence Wu, Rupangi C. Vasavada, Kai Hao Yang et al. · Journal of Biological Chemistry · 1996 · 147 citations · Full text

, , +16

Molecular Cloning, Genomic Organization, and Expression of a C-Type (Manduca sexta-Type) Allatostatin Preprohormone from Drosophila melanogaster

Michael P. Williamson, Camilla Lenz, Åsa M.E. Winther et al. · Biochemical and Biophysical Research Communications · 2001 · 137 citations

, , +7

A relaxin-like peptide purified from radial nerves induces oocyte maturation and ovulation in the starfish, <i>Asterina pectinifera</i>

Masatoshi Mita, Michiyasu Yoshikuni, Kaoru Ohno et al. · Proceedings of the National Academy of Sciences · 2009 · 134 citations · Full text

, , +17

Molecular cloning and functional expression of the first insect FMRFamide receptor

Giuseppe Cazzamali, Cornelis J.P. Grimmelikhuijzen · Proceedings of the National Academy of Sciences · 2002 · 122 citations

, , +12

A New Prosomatostatin-Derived Peptide Reveals a Pattern for Prohormone Cleavage at Monobasic Sites

Robert Benoit, Nicholas Ling, Frederick Esch · Science · 1987 · 120 citations

, , +17

1–5 of 39

Authors

148

  1. CJ
    Cornelis J.P. Grimmelikhuijzen

    University of Copenhagen, Denmark

    4 publications · 416 citations

    4

    h-index

  2. JE
    Jack E. Dixon

    University of Michigan, United States

    3 publications · 177 citations

    3

    h-index

  3. MP
    Michael P. Williamson

    University of Sheffield, United Kingdom

    3 publications · 294 citations

    3

    h-index

  4. RM
    Ronald M. Lechan

    Tufts Medical Center, United States

    3 publications · 163 citations

    3

    h-index

  5. HJ
    Hans Jörnvall

    Karolinska Institutet, Sweden

    2 publications · 84 citations

    2

    h-index

1–5 of 148

Institutions

60

  1. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    12 publications

    1.2K citations

  2. Tufts Medical Center

    Boston, United States

    3 h-index

    6 publications

    346 citations

  3. Universität Hamburg

    Hamburg, Germany

    3 h-index

    6 publications

    295 citations

  4. Radboud University Nijmegen

    Nijmegen, The Netherlands

    2 h-index

    6 publications

    296 citations

  5. Karolinska Institutet

    Stockholm, Sweden

    2 h-index

    9 publications

    397 citations

  6. University of Würzburg

    Würzburg, Germany

    2 h-index

    12 publications

    687 citations

  7. Purdue University West Lafayette

    West Lafayette, United States

    2 h-index

    6 publications

    306 citations

  8. Université Paris Cité

    Paris, France

    2 h-index

    5 publications

    288 citations

1–8 of 60

Venues

  1. Journal of Biological Chemistry

    JBC · 7 publications · 425 citations

    7

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 439 citations

    5

    h-index

  3. Endocrinology

    3 publications · 125 citations

    3

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 3 publications · 266 citations

    3

    h-index

  5. FEBS Letters

    2 publications · 87 citations

    2

    h-index

1–5