Concepedia

Precursors Supply Optimization

Precursors Supply Optimization is a metabolic engineering strategy that systematically enhances the intracellular availability of key biochemical intermediates required for amino acid biosynthesis by regulating flux distribution, gene expression, and substrate utilization to maximize yield and efficiency.

19

Publications

1.1K

Citations

104

Authors

34

Institutions

Publications per year

2017–2026

12

Parents

Publications

19

Engineering yeast for high-level production of stilbenoid antioxidants

Mingji Li, Konstantin Schneider, Mette Kristensen et al. · Scientific Reports · 2016 · 168 citations · Full text

, , +17

Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae

Yun Chen, Jichen Bao, Il‐Kwon Kim et al. · Metabolic Engineering · 2014 · 164 citations

, , +17

Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae

Gionata Scalcinati, Siavash Partow, Verena Siewers et al. · Microbial Cell Factories · 2012 · 152 citations · Full text

, , +17

Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control

Bin Shen, Pingping Zhou, Jiao Xue et al. · Nature Communications · 2020 · 93 citations · Full text

, , +16

Optimization of the IPP Precursor Supply for the Production of Lycopene, Decaprenoxanthin and Astaxanthin by Corynebacterium glutamicum

Sabine A. E. Heider, Natalie K. Wolf, Arne D. Hofemeier et al. · Frontiers in Bioengineering and Biotechnology · 2014 · 85 citations · Full text

, , +17

1–5 of 19

Authors

104

  1. JN
    Jens Nielsen

    Chalmers University of Technology, Sweden

    3 publications · 484 citations

    3

    h-index

  2. VF
    Volker F. Wendisch

    Bielefeld University, Germany

    2 publications · 104 citations

    2

    h-index

  3. TC
    Tao Chen

    Tianjin University, China

    2 publications · 67 citations

    2

    h-index

  4. VS
    Verena Siewers

    Chalmers University of Technology, Sweden

    2 publications · 316 citations

    2

    h-index

  5. IB
    Irina Borodina

    Technical University of Denmark, Denmark

    2 publications · 226 citations

    2

    h-index

1–5 of 104

Institutions

34

  1. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    14 publications

    715 citations

  2. Chalmers University of Technology

    Gothenburg, Sweden

    3 h-index

    10 publications

    1.6K citations

  3. Tianjin University

    Tianjin, China

    3 h-index

    12 publications

    458 citations

  4. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    11 publications

    1.2K citations

  5. Tianjin Institute of Industrial Biotechnology

    Tianjin, China

    2 h-index

    10 publications

    526 citations

  6. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    11 publications

    1.2K citations

  7. Bielefeld University

    Bielefeld, Germany

    2 h-index

    9 publications

    501 citations

  8. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    3 publications

    145 citations

1–8 of 34

Venues

  1. ACS Synthetic Biology

    2 publications · 87 citations

    2

    h-index

  2. Metabolic Engineering

    2 publications · 221 citations

    2

    h-index

  3. Bioresource Technology

    1 publications · 22 citations

    1

    h-index

  4. Journal of Fermentation and Bioengineering

    1 publications · 32 citations

    1

    h-index

  5. Bioprocess and Biosystems Engineering

    1 publications · 18 citations

    1

    h-index

1–5