Concepedia

Pre-initiation Complex Formation

Pre-Initiation Complex Formation is a molecular assembly process in DNA replication wherein the origin recognition complex, Cdc6, Cdt1, and minichromosome maintenance proteins cooperatively bind to replication origins to license them for subsequent initiation of DNA synthesis.

212

Publications

12.9K

Citations

953

Authors

333

Institutions

Publications per year

2017–2026

42

Parents

Publications

212

Genome-wide structure and organization of eukaryotic pre-initiation complexes

Ho Sung Rhee, B. Franklin Pugh · Nature · 2012 · 542 citations

, , +14

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

Julie H. Cocker, Simonetta Piatti, Corrado Santocanale et al. · Nature · 1996 · 358 citations

, , +16

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

Domenico Maiorano, Jacques Moreau, Marcel Méchali · Nature · 2000 · 346 citations

, , +12

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

Lee Zou, Bruce Stillman · Science · 1998 · 324 citations

, , +17

Eukaryotic activators function during multiple steps of preinitiation complex assembly

Bob K. Choy, Michael R. Green · Nature · 1993 · 309 citations

, , +13

1–5 of 212

Authors

953

  1. HO
    Harry O. Voorma

    Utrecht University, Netherlands

    6 publications · 230 citations

    6

    h-index

  2. LS
    Linda Spremulli

    University of North Carolina at Chapel Hill, United States

    6 publications · 257 citations

    6

    h-index

  3. CO
    Claudio O. Gualerzi

    Università di Camerino, Italy

    5 publications · 270 citations

    5

    h-index

  4. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    5 publications · 213 citations

    5

    h-index

  5. LB
    Leendert Bosch

    Leiden University, Netherlands

    4 publications · 75 citations

    4

    h-index

1–5 of 953

Institutions

333

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    67 publications

    3.5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    20 publications

    2.2K citations

  3. Harvard University

    Cambridge, United States

    8 h-index

    27 publications

    2.2K citations

  4. Inserm

    Paris, France

    8 h-index

    42 publications

    1.5K citations

  5. University of Oxford

    Oxford, United Kingdom

    8 h-index

    44 publications

    3.2K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    7 h-index

    15 publications

    588 citations

  7. University of Regensburg

    Regensburg, Germany

    6 h-index

    15 publications

    876 citations

  8. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    6 h-index

    33 publications

    1.3K citations

1–8 of 333

Venues

  1. Nucleic Acids Research

    37 publications · 1.4K citations

    24

    h-index

  2. Journal of Biological Chemistry

    JBC · 28 publications · 1.5K citations

    20

    h-index

  3. Nature Communications

    10 publications · 623 citations

    10

    h-index

  4. European Journal of Biochemistry

    EJB · 9 publications · 272 citations

    9

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 514 citations

    8

    h-index

1–5