Concepedia

Pralidoxime Efficacy

Pralidoxime Efficacy is a quantitative measure within pharmacological research that denotes the capacity of pralidoxime to reactivate acetylcholinesterase inhibited by organophosphate compounds, thereby restoring enzymatic function and mitigating neurotoxic effects.

133

Publications

4.1K

Citations

428

Authors

168

Institutions

Publications per year

2017–2026

13

Parents

Publications

133

Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial

Michael Eddleston, Peter Eyer, Franz Worek et al. · PLoS Medicine · 2009 · 169 citations · Full text

, , +15

Does pralidoxime affect outcome of management in acute organophosphorus poisoning?

H.J. de Silva, R. Wijewickrema, N Senanayake · The Lancet · 1992 · 152 citations

, , +7

Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds

Franz Worek, R. Widmann, O. Knopff et al. · Archives of Toxicology · 1998 · 136 citations

, , +14

Specification of the Structure of Oximes Able to Reactivate Tabun‐Inhibited Acetylcholinesterase

Kamil Kuča, Jiřı́ Kassa · Basic & Clinical Pharmacology & Toxicology · 2004 · 117 citations · Full text

, , +16

A Comparison of the Ability of a New Bispyridinium Oxime—1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane Dibromide and Currently used Oximes to Reactivate Nerve Agent-inhibited Rat Brain Acetylcholinesterase by<i>In Vitro</i>Methods

Kamil Kuča, Jiřı́ Kassa · Journal of Enzyme Inhibition and Medicinal Chemistry · 2003 · 116 citations

, , +15

1–5 of 133

Authors

428

  1. KK
    Kamil Kuča

    University of Hradec Králové, Czechia

    27 publications · 1K citations

    19

    h-index

  2. GP
    Georg Petroianu

    United Arab Emirates University, United Arab Emirates

    16 publications · 482 citations

    14

    h-index

  3. SM
    Syed M. Nurulain

    United Arab Emirates University, United Arab Emirates

    11 publications · 323 citations

    10

    h-index

  4. JK
    Jiřı́ Kassa

    Jan Evangelista Purkyně Military Medical Academy, Czechia

    9 publications · 510 citations

    9

    h-index

  5. MY
    M. Y. Hasan

    United Arab Emirates University, United Arab Emirates

    8 publications · 201 citations

    8

    h-index

1–5 of 428

Institutions

168

  1. University of Defence

    Brno, Czechia

    16 h-index

    38 publications

    1.2K citations

  2. United Arab Emirates University

    Al Ain, United Arab Emirates

    13 h-index

    51 publications

    1.7K citations

  3. Jan Evangelista Purkyně Military Medical Academy

    Hradec Králové, Czechia

    7 h-index

    10 publications

    689 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    29 publications

    491 citations

  5. Université Paris Cité

    Paris, France

    5 h-index

    14 publications

    205 citations

  6. Institut für Pharmakologie und Toxikologie der Bundeswehr

    Munich, Germany

    5 h-index

    9 publications

    301 citations

  7. Inserm

    Paris, France

    5 h-index

    16 publications

    282 citations

  8. Military Institute of Engineering

    Rio de Janeiro, Brazil

    4 h-index

    9 publications

    263 citations

1–8 of 168

Venues

  1. Journal of Applied Toxicology

    14 publications · 465 citations

    11

    h-index

  2. PubMed

    Repository · 9 publications · 316 citations

    9

    h-index

  3. 5

    h-index

  4. JAMA

    5 publications · 227 citations

    5

    h-index

  5. Toxicology Letters

    4 publications · 53 citations

    4

    h-index

1–5