Concepedia

Population-based Dose Optimization

Population-Based Dose Optimization is a pharmacogenomic framework that systematically tailors drug dosing regimens to demographic and genetic characteristics of populations to maximize therapeutic efficacy and minimize adverse effects at the group level.

9

Publications

265

Citations

33

Authors

13

Institutions

Publications per year

2017–2026

1

Parents

Publications

9

Optimization of warfarin dose by population-specific pharmacogenomic algorithm

Addepalli Pavani, Shaik Mohammad Naushad, Yedluri Rupasree et al. · The Pharmacogenomics Journal · 2011 · 58 citations

, , +14

Optimal Design of a Population Pharmacodynamic Experiment for Ivabradine

Stephen B. Duffull, France Mentré, Leon Aarons · Pharmaceutical Research · 2001 · 39 citations

, , +12

Population pharmacokinetics of plasma‐derived factor IX: procedures for dose individualization

Ari Brekkan, Erik Berntorp, K L Jensen et al. · Journal of Thrombosis and Haemostasis · 2016 · 38 citations

, , +16

Optimizing phase II of drug development for disease‐modifying compounds

Jeffrey L. Cummings · Alzheimer s & Dementia · 2008 · 30 citations

, , +14

Population approaches in drug development

Leon Aarons, L. P. Balant, F. Mentr� et al. · European Journal of Clinical Pharmacology · 1994 · 27 citations

, , +10

1–5 of 9

Authors

33

  1. LA
    Leon Aarons

    University of Manchester, United Kingdom

    2 publications · 66 citations

    2

    h-index

  2. VD
    Victoria Doldàn-Martelli

    Universidad Autónoma de Madrid, Spain

    1 publications · 16 citations

    1

    h-index

  3. AP
    Addepalli Pavani

    Nizam's Institute of Medical Sciences, India

    1 publications · 58 citations

    1

    h-index

  4. TR
    T. Ramesh Kumar

    Nizam's Institute of Medical Sciences, India

    1 publications · 58 citations

    1

    h-index

  5. DG
    David G. Míguez

    Universidade de Santiago de Compostela, Spain

    1 publications · 16 citations

    1

    h-index

1–5 of 33

Institutions

13

  1. Inserm

    Paris, France

    2 h-index

    2 publications

    66 citations

  2. University of Manchester

    Manchester, United Kingdom

    2 h-index

    4 publications

    132 citations

  3. Skåne University Hospital

    Lund, Sweden

    1 h-index

    2 publications

    76 citations

  4. Sorbonne Université

    Paris, France

    1 h-index

    1 publications

    39 citations

  5. Pitié-Salpêtrière Hospital

    Paris, France

    1 h-index

    1 publications

    39 citations

  6. Uppsala University

    Uppsala, Sweden

    1 h-index

    3 publications

    114 citations

  7. Cairo University

    Giza, Egypt

    1 h-index

    4 publications

    88 citations

  8. Nizam's Institute of Medical Sciences

    Hyderabad, India

    1 h-index

    8 publications

    464 citations

1–8 of 13

Venues

  1. European Journal of Clinical Pharmacology

    1 publications · 27 citations

    1

    h-index

  2. Pharmaceutical Research

    1 publications · 39 citations

    1

    h-index

  3. Journal of Thrombosis and Haemostasis

    JTH · 1 publications · 38 citations

    1

    h-index

  4. Alzheimer s & Dementia

    1 publications · 30 citations

    1

    h-index

  5. The Pharmacogenomics Journal

    1 publications · 58 citations

    1

    h-index

1–5