Concepedia

Population Dose-response Variability

Population Dose-Response Variability is a quantitative construct that characterizes the variation in biological or toxicological response to a given dose of an agent across individuals within a population, distinguishing it from individual-level dose-response models by accounting for inter-individual heterogeneity in susceptibility, exposure, or pharmacokinetic and pharmacodynamic processes.

5

Publications

267

Citations

33

Authors

12

Institutions

Publications per year

2017–2026

1

Parents

Publications

5

Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment

Richard Judson, Robert J. Kavlock, R. Woodrow Setzer et al. · Chemical Research in Toxicology · 2011 · 203 citations

, , +17

A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures

Lucie C. Ford, Suji Jang, Zunwei Chen et al. · Toxics · 2022 · 23 citations · Full text

, , +16

DNA damage in different Eisenia andrei coelomocytes sub-populations after in vitro exposure to hydrogen peroxide

Laura Mincarelli, Costantino Vischetti, John A. Craft et al. · SpringerPlus · 2016 · 19 citations · Full text

, , +17

Comparison of Different Methods to Evaluate Population Dose–Response and Relative Potency: Importance of Interoccasion Variability

Richard L. Lalonde, Danièle Ouellet, Ebi K. Kimanani et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1999 · 12 citations

, , +12

Lurasidone Dose Response in Bipolar Depression: A Population Dose-response Analysis

Sunny Chapel, Yu‐Yuan Chiu, Jay Hsu et al. · Clinical Therapeutics · 2015 · 10 citations

, , +14

1–5 of 5

Authors

33

  1. PJ
    Paul J. Gallins

    Center for Human Genetics, United States

    1 publications · 23 citations

    1

    h-index

  2. MT
    Matthew T. Martin

    Environmental Protection Agency, United States

    1 publications · 203 citations

    1

    h-index

  3. RJ
    Robert J. Kavlock

    Environmental Protection Agency, United States

    1 publications · 203 citations

    1

    h-index

  4. IR
    Ivan Rusyn

    University of North Carolina at Chapel Hill, United States

    1 publications · 23 citations

    1

    h-index

  5. KA
    Keith A. Houck

    Environmental Protection Agency, United States

    1 publications · 203 citations

    1

    h-index

1–5 of 33

Institutions

12

  1. North Carolina State University

    Raleigh, United States

    1 h-index

    3 publications

    69 citations

  2. Vion Pharmaceuticals (United States)

    New Haven, United States

    1 h-index

    4 publications

    40 citations

  3. Environmental Protection Agency

    Washington, United States

    1 h-index

    8 publications

    1.6K citations

  4. Dura Biotech (United States)

    Storrs, United States

    1 h-index

    2 publications

    24 citations

  5. Research Triangle Park Foundation

    Durham, United States

    1 h-index

    8 publications

    1.6K citations

  6. Québec International

    Québec, Canada

    1 h-index

    1 publications

    12 citations

  7. Sunovion (United States)

    Marlborough, United States

    1 h-index

    4 publications

    40 citations

  8. The Hamner Institutes for Health Sciences

    Durham, United States

    1 h-index

    2 publications

    406 citations

1–8 of 12

Venues

  1. Chemical Research in Toxicology

    1 publications · 203 citations

    1

    h-index

  2. Clinical Therapeutics

    1 publications · 10 citations

    1

    h-index

  3. 1

    h-index

  4. Toxics

    1 publications · 23 citations

    1

    h-index

  5. SpringerPlus

    1 publications · 19 citations

    1

    h-index

1–5