Concepedia

Polypyrimidine Tract Recognition

Polypyrimidine Tract Recognition is a molecular biology mechanism that identifies the conserved pyrimidine-rich sequence element downstream of 3' splice sites during pre-mRNA splicing to facilitate accurate spliceosome assembly and exon definition.

295

Publications

20.6K

Citations

995

Authors

305

Institutions

Publications per year

2017–2026

19

Parents

Publications

295

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

Ravinder Singh, Juan Valcárcel, Michael R. Green · Science · 1995 · 541 citations

, , +15

Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation

Florian C. Oberstrass, Sigrid Auweter, Michèle C. Erat et al. · Science · 2005 · 464 citations

, , +16

Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay

Matthew Wollerton, Clare Gooding, Eric J. Wagner et al. · Molecular Cell · 2004 · 414 citations · Full text

, , +13

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.

Mariano A. García-Blanco, Sharon F. Jamison, P A Sharp · Genes & Development · 1989 · 347 citations · Full text

, , +6

Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein

Vadim Markovtsov, Julia Nikolic, Joseph Goldman et al. · Molecular and Cellular Biology · 2000 · 317 citations

, , +17

1–5 of 295

Authors

995

  1. CW
    Christopher W. J. Smith

    University of Cambridge, United Kingdom

    15 publications · 1.6K citations

    14

    h-index

  2. DL
    Douglas L. Black

    University of California, Los Angeles, United States

    11 publications · 2.1K citations

    11

    h-index

  3. JV
    Juan Valcárcel

    Centre for Genomic Regulation, Spain

    11 publications · 1.5K citations

    11

    h-index

  4. CL
    Clara L. Kielkopf

    University of Rochester, United States

    10 publications · 515 citations

    10

    h-index

  5. RS
    Ravinder Singh

    University of Colorado Boulder, United States

    8 publications · 1K citations

    8

    h-index

1–5 of 995

Institutions

305

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    31 h-index

    87 publications

    17K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    20 h-index

    73 publications

    7.5K citations

  3. University of California, Los Angeles

    Los Angeles, United States

    13 h-index

    51 publications

    5.9K citations

  4. Imperial College London

    London, United Kingdom

    10 h-index

    34 publications

    1.5K citations

  5. University of Rochester

    Rochester, United States

    8 h-index

    38 publications

    1.6K citations

  6. Columbia University

    New York, United States

    8 h-index

    20 publications

    2.1K citations

  7. Indian Institute of Science Bangalore

    Bengaluru, India

    8 h-index

    25 publications

    706 citations

  8. European Molecular Biology Laboratory

    Heidelberg, Germany

    8 h-index

    19 publications

    1.8K citations

1–8 of 305

Venues

  1. Nucleic Acids Research

    43 publications · 2.4K citations

    30

    h-index

  2. Molecular and Cellular Biology

    MCB · 25 publications · 2.4K citations

    23

    h-index

  3. RNA

    26 publications · 1.4K citations

    21

    h-index

  4. Journal of Biological Chemistry

    JBC · 21 publications · 1.2K citations

    20

    h-index

  5. Journal of Virology

    JVI · 16 publications · 1.2K citations

    15

    h-index

1–5