Concepedia

Polymerase-dna Binding

Polymerase-DNA Binding is a biochemical interaction in which a DNA polymerase enzyme specifically associates with a DNA template-primer substrate, forming a stable complex that enables the catalytic addition of nucleotides during DNA replication or repair.

1.4K

Publications

85.4K

Citations

3.7K

Authors

835

Institutions

Publications per year

2017–2026

72

Parents

Publications

1.4K

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

David L. Ollis, P. Brick, R. Hamlin et al. · Nature · 1985 · 849 citations

, , +14

Interaction of Human DNA Polymerase η with Monoubiquitinated PCNA

Patricia Kannouche, Jonathan Wing, Alan R. Lehmann · Molecular Cell · 2004 · 842 citations · Full text

, , +11

STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP

H Pelletier, M.R. Sawaya, Amalendra Kumar et al. · 1994 · 693 citations

, , +17

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation

The EMBO Journal · 1998 · 689 citations · Full text

, , +17

Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions

Robert E. Johnson, M. Todd Washington, Lajos Haracska et al. · Nature · 2000 · 627 citations

, , +13

1–5 of 1.4K

Authors

3.7K

  1. SH
    Samuel H. Wilson

    National Institutes of Health, United States

    55 publications · 5.9K citations

    36

    h-index

  2. LB
    Luis Blanco

    Centro de Biología Molecular Severo Ochoa, Spain

    26 publications · 2K citations

    23

    h-index

  3. WA
    William A. Beard

    National Institute of Environmental Health Sciences, United States

    26 publications · 1.9K citations

    23

    h-index

  4. MS
    Margarita Salas

    Centro de Biología Molecular Severo Ochoa, Spain

    28 publications · 1.5K citations

    20

    h-index

  5. KS
    Kengo Sakaguchi

    Tokyo University of Science, Japan

    24 publications · 928 citations

    19

    h-index

1–5 of 3.7K

Institutions

835

  1. National Institutes of Health

    Bethesda, United States

    43 h-index

    222 publications

    15.7K citations

  2. National Institute of Environmental Health Sciences

    Durham, United States

    36 h-index

    172 publications

    14.5K citations

  3. Yale University

    New Haven, United States

    35 h-index

    194 publications

    18.2K citations

  4. Harvard University

    Cambridge, United States

    32 h-index

    124 publications

    9.2K citations

  5. The University of Texas Medical Branch at Galveston

    Galveston, United States

    29 h-index

    133 publications

    13.1K citations

  6. Stanford University

    Stanford, United States

    28 h-index

    91 publications

    8.1K citations

  7. Centro de Biología Molecular Severo Ochoa

    Madrid, Spain

    26 h-index

    157 publications

    11.3K citations

  8. Universidad Autónoma de Madrid

    Madrid, Spain

    25 h-index

    151 publications

    10.6K citations

1–8 of 835

Venues

  1. Journal of Biological Chemistry

    JBC · 241 publications · 16.5K citations

    73

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 87 publications · 7K citations

    50

    h-index

  3. Journal of Molecular Biology

    JMB · 87 publications · 5.9K citations

    43

    h-index

  4. Biochemistry

    121 publications · 5.9K citations

    42

    h-index

  5. Nucleic Acids Research

    120 publications · 5.7K citations

    41

    h-index

1–5