Concepedia

Polymerase Stalling

Polymerase Stalling is a molecular biological phenomenon in which DNA polymerase temporarily halts its progression along a DNA template during replication due to structural, chemical, or sequence-specific impediments that interfere with nucleotide incorporation or translocation.

68

Publications

6.1K

Citations

366

Authors

148

Institutions

Publications per year

2017–2026

21

Parents

Publications

68

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Goran Kokić, Hauke S. Hillen, Dimitry Tegunov et al. · Nature Communications · 2021 · 630 citations · Full text

, , +17

Enhancer loops appear stable during development and are associated with paused polymerase

Yad Ghavi-Helm, Felix A. Klein, Tibor Pakozdi et al. · Nature · 2014 · 550 citations · Full text

, , +12

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in <i>Drosophila</i>

Sergei Nechaev, David C. Fargo, Gilberto dos Santos et al. · Science · 2009 · 434 citations

, , +17

Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5

Rushad Pavri, Anna Gazumyan, Mila Janković et al. · Cell · 2010 · 371 citations · Full text

, , +14

Replication slippage involves DNA polymerase pausing and dissociation

Enrique Viguera · The EMBO Journal · 2001 · 370 citations · Full text

, , +12

1–5 of 68

Authors

366

  1. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    3 publications · 831 citations

    3

    h-index

  2. SP
    Satya Prakash

    The University of Texas Medical Branch at Galveston, United States

    3 publications · 307 citations

    3

    h-index

  3. LP
    Louise Prakash

    The University of Texas Medical Branch at Galveston, United States

    3 publications · 307 citations

    3

    h-index

  4. KA
    Kristin A. Eckert

    Pennsylvania State University, United States

    3 publications · 203 citations

    3

    h-index

  5. RE
    Robert E. Johnson

    The University of Texas Medical Branch at Galveston, United States

    3 publications · 307 citations

    3

    h-index

1–5 of 366

Institutions

148

  1. Pennsylvania State University

    State College, United States

    7 h-index

    21 publications

    1.3K citations

  2. Inserm

    Paris, France

    4 h-index

    7 publications

    720 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    5 publications

    1.2K citations

  4. The University of Texas Medical Branch at Galveston

    Galveston, United States

    3 h-index

    12 publications

    1.2K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    6 publications

    256 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    10 publications

    502 citations

  7. Université Paris Cité

    Paris, France

    3 h-index

    8 publications

    297 citations

  8. National Institutes of Health

    Bethesda, United States

    3 h-index

    14 publications

    3.9K citations

1–8 of 148

Venues

  1. Nucleic Acids Research

    8 publications · 408 citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 494 citations

    6

    h-index

  3. Journal of Biological Chemistry

    JBC · 5 publications · 454 citations

    5

    h-index

  4. Molecular Cell

    4 publications · 561 citations

    4

    h-index

  5. Journal of Molecular Biology

    JMB · 4 publications · 171 citations

    4

    h-index

1–5