Concepedia

Polyene Antifungals

Polyene Antifungals is a class of antifungal agents characterized by a macrocyclic lactone ring with multiple conjugated double bonds that selectively bind to ergosterol in fungal cell membranes, thereby forming pores that disrupt membrane integrity and lead to cell death.

350

Publications

17K

Citations

1.3K

Authors

402

Institutions

Publications per year

2017–2026

56

Variants

Polyene Antifungal

Parents

Publications

350

<i>Candida albicans</i> Biofilms Produce Antifungal-Tolerant Persister Cells

Michael D. LaFleur, Carol A. Kumamoto, Kim Lewis · Antimicrobial Agents and Chemotherapy · 2006 · 505 citations · Full text

, , +17

Combination Polyene‐Caspofungin Treatment of Rhino‐Orbital‐Cerebral Mucormycosis

Caitlin Reed, Richard E. Bryant, Ashraf S. Ibrahim et al. · Clinical Infectious Diseases · 2008 · 493 citations · Full text

, , +11

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug

Ana Cecilia Mesa-Arango, Liliana Scorzoni, Óscar Zaragoza · Frontiers in Microbiology · 2012 · 308 citations · Full text

, , +16

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway

Trygve Brautaset, Olga N. Sekurova, Håvard Sletta et al. · Chemistry & Biology · 2000 · 290 citations · Full text

, , +15

Chemistry and biology of the polyene macrolide antibiotics.

J M Hamilton-Miller · Bacteriological Reviews · 1973 · 277 citations · Full text

, , +12

1–5 of 350

Authors

1.3K

  1. EB
    Edward Borowski

    University of Gdańsk, Poland

    10 publications · 335 citations

    10

    h-index

  2. SB
    Sergey B. Zotchev

    Norwegian University of Science and Technology, Norway

    8 publications · 665 citations

    8

    h-index

  3. JO
    J. O. Lampen

    Rutgers, The State University of New Jersey, United States

    7 publications · 549 citations

    7

    h-index

  4. GM
    Gerald Medoff

    Washington University in St. Louis, United States

    7 publications · 384 citations

    7

    h-index

  5. SE
    Svetlana E. Solovieva

    Gause Institute of New Antibiotics Russian Academy of Medical Sciences, Russia

    6 publications · 212 citations

    6

    h-index

1–5 of 1.3K

Institutions

402

  1. Rutgers, The State University of New Jersey

    New Brunswick, United States

    12 h-index

    43 publications

    2.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    32 publications

    1.5K citations

  3. Washington University in St. Louis

    St Louis, United States

    10 h-index

    31 publications

    2.1K citations

  4. Gause Institute of New Antibiotics Russian Academy of Medical Sciences

    Moscow, Russia

    9 h-index

    48 publications

    1.9K citations

  5. University of Illinois Urbana-Champaign

    Urbana, United States

    9 h-index

    50 publications

    3.7K citations

  6. Gdańsk University of Technology

    Gdansk, Poland

    9 h-index

    50 publications

    1.9K citations

  7. Norwegian University of Science and Technology

    Trondheim, Norway

    8 h-index

    28 publications

    2.6K citations

  8. Maria Curie-Skłodowska University

    Lublin, Poland

    7 h-index

    20 publications

    645 citations

1–8 of 402

Venues

  1. PubMed

    Repository · 27 publications · 1.1K citations

    19

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 29 publications · 1.8K citations

    18

    h-index

  3. The Journal of Antibiotics

    14 publications · 296 citations

    11

    h-index

  4. Canadian Journal of Microbiology

    8 publications · 285 citations

    8

    h-index

  5. Journal of Natural Products

    8 publications · 253 citations

    8

    h-index

1–5