Concepedia

Polyadenylation-dependent Termination

Polyadenylation-Dependent Termination is a transcription termination mechanism in RNA Polymerase II-mediated gene expression wherein the cleavage and polyadenylation of the nascent mRNA transcript trigger the dissociation of the polymerase from the DNA template.

66

Publications

4.2K

Citations

258

Authors

107

Institutions

Publications per year

2017–2026

14

Variants

Polyadenylation-dependent Transcription Termination

Parents

Publications

66

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

John S. Logan, Erik Falck-Pedersen, James Darnell et al. · Proceedings of the National Academy of Sciences · 1987 · 265 citations · Full text

, , +17

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3′ processing and transcription termination

Syuzo Kaneko, Orit Rozenblatt–Rosen, Matthew Meyerson et al. · Genes & Development · 2007 · 175 citations · Full text

, , +17

The Integrator complex controls the termination of transcription at diverse classes of gene targets

Jeffrey R. Skaar, Andrea L. Ferris, Xiaolin Wu et al. · Cell Research · 2015 · 164 citations · Full text

, , +17

Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors

Yung-Chia Ariel Chen, Evelyn Stuwe, Yicheng Luo et al. · Molecular Cell · 2016 · 164 citations · Full text

, , +14

Evolutionarily Conserved Interaction between CstF-64 and PC4 Links Transcription, Polyadenylation, and Termination

Olga Calvo, James L. Manley · Molecular Cell · 2001 · 161 citations · Full text

, , +10

1–5 of 66

Authors

258

  1. CM
    Claire Moore

    Tufts University, United States

    5 publications · 172 citations

    6

    h-index

  2. HG
    Harold G. Martinson

    University of California, Los Angeles, United States

    6 publications · 242 citations

    6

    h-index

  3. LE
    Linda E. Hyman

    Tulane University, United States

    4 publications · 116 citations

    4

    h-index

  4. FB
    François Bachand

    Université de Sherbrooke, Canada

    2 publications · 115 citations

    3

    h-index

  5. EF
    Erik Falck-Pedersen

    Cornell University, United States

    3 publications · 368 citations

    3

    h-index

1–5 of 258

Institutions

107

  1. University of California, Los Angeles

    Los Angeles, United States

    8 h-index

    26 publications

    857 citations

  2. Tufts University

    Medford, United States

    6 h-index

    12 publications

    390 citations

  3. University of Oxford

    Oxford, United Kingdom

    5 h-index

    22 publications

    1.9K citations

  4. University of Toronto

    Toronto, Canada

    3 h-index

    8 publications

    1.1K citations

  5. Université de Sherbrooke

    Sherbrooke, Canada

    3 h-index

    11 publications

    622 citations

  6. Johns Hopkins University

    Baltimore, United States

    3 h-index

    12 publications

    1.3K citations

  7. Cornell University

    Ithaca, United States

    3 h-index

    6 publications

    309 citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    4 publications

    472 citations

1–8 of 107

Venues

  1. Molecular and Cellular Biology

    MCB · 19 publications · 1K citations

    19

    h-index

  2. Genes & Development

    6 publications · 601 citations

    6

    h-index

  3. Molecular Cell

    5 publications · 681 citations

    5

    h-index

  4. Nucleic Acids Research

    4 publications · 137 citations

    5

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 324 citations

    3

    h-index

1–5