Polyadenylation Factor Function is a molecular mechanism that specifies the recruitment and activity of protein complexes responsible for cleaving pre-mRNA and adding a poly(A) tail during transcription termination, thereby distinguishing it from other regulatory processes by its essential role in mRNA 3′ end formation and transcript stability.
206
Publications
16.5K
Citations
907
Authors
287
Institutions
Publications per year
2017–2026
34
Parents
Publications
206
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease
Corey R. Mandel, Syuzo Kaneko, Hailong Zhang et al. · Nature · 2006 · 461 citations · Full text
RNA polymerase II is an essential mRNA polyadenylation factor
Yutaka Hirose, James L. Manley · Nature · 1998 · 356 citations
1–5 of 206
Authors
907
- JL
18
h-index
- WK
14
h-index
- CM
13
h-index
- AG
10
h-index
- QQ
9
h-index
1–5 of 907
Institutions
287
Columbia University
New York, United States
19 h-index
59 publications
11.4K citations
University of Basel
Basel, Switzerland
17 h-index
45 publications
5.8K citations
Tufts University
Medford, United States
14 h-index
44 publications
3K citations
Centre National de la Recherche Scientifique
Paris, France
13 h-index
46 publications
3.5K citations
University of Kentucky
Lexington, United States
11 h-index
41 publications
4K citations
Rutgers, The State University of New Jersey
New Brunswick, United States
10 h-index
25 publications
1.8K citations
Howard Hughes Medical Institute
Chevy Chase, United States
8 h-index
28 publications
4.5K citations
University of Oxford
Oxford, United Kingdom
7 h-index
22 publications
3K citations
1–8 of 287
Venues
- Molecular and Cellular Biology
MCB · 27 publications · 2.6K citations
26
h-index
- Nucleic Acids Research
20 publications · 1.2K citations
18
h-index
- Journal of Biological Chemistry
JBC · 18 publications · 977 citations
17
h-index
- RNA
14 publications · 816 citations
14
h-index
- Proceedings of the National Academy of Sciences
PNAS · 12 publications · 1.4K citations
12
h-index
1–5