Concepedia

Podocin Dysfunction

Podocin Dysfunction is a molecular pathophysiological mechanism characterized by impaired function of the podocin protein, a critical slit diaphragm component in renal podocytes, leading to disrupted signaling complexes and compromised glomerular filtration barrier integrity.

93

Publications

6.1K

Citations

610

Authors

220

Institutions

Publications per year

2017–2026

28

Parents

Publications

93

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

Nicolas Boute, Olivier Gribouval, Séverine Roselli et al. · Nature Genetics · 2000 · 1.4K citations

, , +13

Podocyte as the Target for Aldosterone

Shigeru Shibata, Miki Nagase, Shigetaka Yoshida et al. · Hypertension · 2007 · 355 citations

, , +17

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

Jacqueline Ho, Kar Hui Ng, Seymour Rosen et al. · Journal of the American Society of Nephrology · 2008 · 297 citations · Full text

, , +17

Molecular basis of the functionalpodocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains

Tobias B. Huber · Human Molecular Genetics · 2003 · 288 citations · Full text

, , +17

Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Séverine Roselli, Laurence Heidet, Mireille Sich et al. · Molecular and Cellular Biology · 2003 · 262 citations · Full text

, , +15

1–5 of 93

Authors

610

  1. CA
    Corinne Antignac

    Inserm, France

    8 publications · 2.2K citations

    8

    h-index

  2. HK
    Hiroshi Kawachi

    Niigata University, Japan

    6 publications · 621 citations

    6

    h-index

  3. GM
    Gian Marco Ghiggeri

    Istituto Giannina Gaslini, Italy

    5 publications · 421 citations

    5

    h-index

  4. MD
    Marco Di Duca

    Istituto Giannina Gaslini, Italy

    4 publications · 380 citations

    4

    h-index

  5. GC
    Gianluca Caridi

    Istituto Giannina Gaslini, Italy

    4 publications · 380 citations

    4

    h-index

1–5 of 610

Institutions

220

  1. Inserm

    Paris, France

    8 h-index

    42 publications

    14.3K citations

  2. Université Paris Cité

    Paris, France

    6 h-index

    34 publications

    14.4K citations

  3. Niigata University

    Niigata, Japan

    5 h-index

    18 publications

    3K citations

  4. Istituto Giannina Gaslini

    Genoa, Italy

    5 h-index

    37 publications

    4.2K citations

  5. Hôpital Necker-Enfants Malades

    Paris, France

    5 h-index

    14 publications

    3.2K citations

  6. University of Cologne

    Cologne, Germany

    4 h-index

    32 publications

    755 citations

  7. Washington University in St. Louis

    St Louis, United States

    4 h-index

    12 publications

    1.1K citations

  8. Hadassah Medical Center

    Jerusalem, Israel

    3 h-index

    4 publications

    396 citations

1–8 of 220

Venues

  1. 9

    h-index

  2. Journal of the American Society of Nephrology

    6 publications · 662 citations

    6

    h-index

  3. Kidney International

    5 publications · 321 citations

    5

    h-index

  4. PLoS ONE

    3 publications · 240 citations

    3

    h-index

  5. Scientific Reports

    3 publications · 88 citations

    3

    h-index

1–5