Concepedia

Plasmid Size Optimization

Plasmid Size Optimization is a methodological strategy in molecular biology that entails the systematic reduction or adjustment of plasmid DNA length to enhance transformation efficiency, plasmid stability, and recombinant protein expression while minimizing non-essential genetic elements.

18

Publications

1.5K

Citations

65

Authors

27

Institutions

Publications per year

2017–2026

2

Parents

Publications

18

A multiple plasmid-containing Escherichia coli strain: Convenient source of size reference plasmid molecules

Francis L. Macrina, Dennis J. Kopecko, Kevin R. Jones et al. · Plasmid · 1978 · 800 citations

, , +15

Bacterial fitness and plasmid loss: the importance of culture conditions and plasmid size

Malcolm A Smith, Michael Bidochka · Canadian Journal of Microbiology · 1998 · 150 citations

, , +17

Minimal size plasmids containing an M13 origin for production of single-strand transducing particles.

Arnold I. Levinson, Donald M. Silver, Brian Seed · PubMed · 1984 · 88 citations

, , +17

Effects of recombinant plasmid size on cellular processes in Escherichia coli

U.Eong Cheah, William A. Weigand, Benjamin C. Stark · Plasmid · 1987 · 83 citations

, , +16

Plasmid DNA Size Does Affect Nonviral Gene Delivery Efficiency in Stem Cells

Sofia Ribeiro, Juergen Mairhofer, Catarina Madeira et al. · Cellular Reprogramming · 2012 · 68 citations

, , +17

1–5 of 18

Authors

65

  1. MB
    Michael Bidochka

    Brock University, Canada

    2 publications · 168 citations

    2

    h-index

  2. BC
    Benjamin C. Stark

    Illinois Institute of Technology, United States

    2 publications · 122 citations

    2

    h-index

  3. JM
    Juergen Mairhofer

    BOKU University, Austria

    1 publications · 68 citations

    1

    h-index

  4. DM
    Donald M. Silver

    Massachusetts General Hospital, United States

    1 publications · 88 citations

    1

    h-index

  5. AK
    Alison Kay

    University College London, United Kingdom

    1 publications · 21 citations

    1

    h-index

1–5 of 65

Institutions

27

  1. Institute for Biotechnology and Bioengineering

    Lisbon, Portugal

    2 h-index

    9 publications

    444 citations

  2. Illinois Institute of Technology

    Chicago, United States

    2 h-index

    7 publications

    405 citations

  3. Maastricht University

    Maastricht, The Netherlands

    1 h-index

    3 publications

    144 citations

  4. National Institute for Environmental Studies

    Tsukuba, Japan

    1 h-index

    6 publications

    354 citations

  5. Arizona State University

    Tempe, United States

    1 h-index

    3 publications

    99 citations

  6. Instituto Superior Técnico

    Lisbon, Portugal

    1 h-index

    3 publications

    36 citations

  7. Houston Methodist

    Houston, United States

    1 h-index

    1 publications

    21 citations

  8. Pennsylvania State University

    State College, United States

    1 h-index

    4 publications

    44 citations

1–8 of 27

Venues

  1. Plasmid

    3 publications · 922 citations

    3

    h-index

  2. Canadian Journal of Microbiology

    2 publications · 168 citations

    2

    h-index

  3. PubMed

    Repository · 2 publications · 108 citations

    2

    h-index

  4. Cellular Reprogramming

    1 publications · 68 citations

    1

    h-index

  5. Journal of Virology

    JVI · 1 publications · 33 citations

    1

    h-index

1–5