Concepedia

Physicochemical Property Filtering

Physicochemical Property Filtering is a computational method that, as a part of drug-likeness assessment, selects or prioritizes compounds based on their adherence to empirically derived ranges of physicochemical properties such as molecular weight, lipophilicity, solubility, and ionization state, thereby distinguishing it from other filtering approaches by focusing exclusively on quantifiable molecular characteristics predictive of pharmacokinetic and pharmacodynamic behavior.

26

Publications

1.5K

Citations

125

Authors

61

Institutions

Publications per year

2017–2026

11

Parents

Publications

26

FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects

David Lagorce, Olivier Spérandio, Hervé Galons et al. · BMC Bioinformatics · 2008 · 263 citations · Full text

, , +15

The Rule of Five Revisited:  Applying Log <i>D</i> in Place of Log <i>P</i> in Drug-Likeness Filters

Sanjivanjit K. Bhal, Karim Kassam, Ian G. Peirson et al. · Molecular Pharmaceutics · 2007 · 219 citations

, , +16

Drug-like Annotation and Duplicate Analysis of a 23-Supplier Chemical Database Totalling 2.7 Million Compounds

Nicolas Baurin, Ruth L. Baker, C. E. Richardson et al. · Journal of Chemical Information and Computer Sciences · 2004 · 115 citations

, , +15

Evaluation of blockbuster drugs under the Rule-of-five

B G Giménez, Maurício Silva dos Santos, Márcio Ferrarini et al. · ˜Die œPharmazie · 2010 · 104 citations · Full text

, , +15

Development of a Method for Evaluating Drug-Likeness and Ease of Synthesis Using a Data Set in Which Compounds Are Assigned Scores Based on Chemists' Intuition

Yuji Takaoka, Yutaka Endo, Susumu Yamanobe et al. · Journal of Chemical Information and Computer Sciences · 2003 · 96 citations

, , +17

1–5 of 26

Authors

125

  1. AR
    Anwar Rayan

    Al-Qasemi Academic College of Education, Israel

    2 publications · 50 citations

    2

    h-index

  2. MP
    Matic Proj

    University of Ljubljana, Slovenia

    1 publications · 23 citations

    1

    h-index

  3. TH
    Tingjun Hou

    Zhejiang University, China

    1 publications · 84 citations

    1

    h-index

  4. MM
    Masahiro Mochizuki

    BoZo Research Center (Japan), Japan

    1 publications · 18 citations

    1

    h-index

  5. TS
    Tanja Schirmeister

    Johannes Gutenberg University Mainz, Germany

    1 publications · 18 citations

    1

    h-index

1–5 of 125

Institutions

61

  1. Rajiv Gandhi University of Health Sciences

    Bengaluru, India

    1 h-index

    3 publications

    39 citations

  2. Bar-Ilan University

    Ramat Gan, Israel

    1 h-index

    1 publications

    22 citations

  3. Saarland University

    Saarbrücken, Germany

    1 h-index

    4 publications

    244 citations

  4. Rice University

    Houston, United States

    1 h-index

    1 publications

    23 citations

  5. West China Hospital of Sichuan University

    Chengdu, China

    1 h-index

    9 publications

    135 citations

  6. University of Ljubljana

    Ljubljana, Slovenia

    1 h-index

    4 publications

    92 citations

  7. University of Leeds

    Leeds, United Kingdom

    1 h-index

    2 publications

    88 citations

  8. Faculdade de Medicina do ABC

    Santo André, Brazil

    1 h-index

    3 publications

    312 citations

1–8 of 61

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 3 publications · 121 citations

    3

    h-index

  2. Journal of Pharmaceutical Sciences

    2 publications · 58 citations

    2

    h-index

  3. ˜Die œPharmazie

    2 publications · 117 citations

    2

    h-index

  4. 2

    h-index

  5. Artificial Intelligence in Medicine

    AIM · 1 publications · 15 citations

    1

    h-index

1–5