Concepedia

Phi-value Analysis

Phi-Value Analysis is a biophysical method used in protein folding studies that quantifies the structure formation in the transition state by comparing the energetic effects of mutations on the folding kinetics and thermodynamic stability, thereby distinguishing the extent of native-like structure in the folding pathway.

60

Publications

3K

Citations

225

Authors

102

Institutions

Publications per year

2017–2026

4

Variants

Phi AnalysisPhi-value Analysis Method

Parents

Publications

60

Transition-state structure as a unifying basis in protein-folding mechanisms: Contact order, chain topology, stability, and the extended nucleus mechanism

Alan R. Fersht · Proceedings of the National Academy of Sciences · 2000 · 326 citations

, , +17

Protein folding by zipping and assembly

S. Banu Ozkan, Guohong Wu, John D. Chodera et al. · Proceedings of the National Academy of Sciences · 2007 · 147 citations · Full text

, , +17

Transition states and the meaning of Phi-values in protein folding kinetics.

S. Banu Ozkan, İvet Bahar, Ken A. Dill · Nature Structural Biology · 2001 · 146 citations

, , +14

Testing protein-folding simulations by experiment: B domain of protein A

Satoshi Sato, Tomasz L. Religa, Valerie Daggett et al. · Proceedings of the National Academy of Sciences · 2004 · 136 citations · Full text

, , +17

Submillisecond events in protein folding.

Bengt Nölting, Ralph Golbik, A.R. Fersht · Proceedings of the National Academy of Sciences · 1995 · 136 citations · Full text

, , +17

1–5 of 60

Authors

225

  1. JC
    Jane Clarke

    University of Cambridge, United Kingdom

    4 publications · 163 citations

    4

    h-index

  2. TR
    Tobin R. Sosnick

    University of Chicago, United States

    3 publications · 81 citations

    3

    h-index

  3. KA
    Ken A. Dill

    University of California, San Francisco, United States

    3 publications · 365 citations

    3

    h-index

  4. PW
    Pernilla Wittung‐Stafshede

    Chalmers University of Technology, Sweden

    3 publications · 85 citations

    3

    h-index

  5. TS
    Tomofumi Santa

    The University of Tokyo, Japan

    2 publications · 119 citations

    2

    h-index

1–5 of 225

Institutions

102

  1. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    15 publications

    871 citations

  2. Rice University

    Houston, United States

    3 h-index

    10 publications

    254 citations

  3. University of Chicago

    Chicago, United States

    3 h-index

    3 publications

    81 citations

  4. University of California, San Francisco

    San Francisco, United States

    3 h-index

    9 publications

    1.1K citations

  5. University of Leeds

    Leeds, United Kingdom

    2 h-index

    7 publications

    332 citations

  6. University of Zurich

    Zurich, Switzerland

    2 h-index

    5 publications

    293 citations

  7. Stanford University

    Stanford, United States

    2 h-index

    3 publications

    199 citations

  8. GTx (United States)

    Memphis, United States

    2 h-index

    2 publications

    39 citations

1–8 of 102

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.2K citations

    12

    h-index

  2. Protein Science

    PS · 8 publications · 237 citations

    8

    h-index

  3. Journal of Molecular Biology

    JMB · 6 publications · 242 citations

    6

    h-index

  4. Journal of Computational Biology

    2 publications · 54 citations

    2

    h-index

  5. Biochemistry

    2 publications · 37 citations

    2

    h-index

1–5