Concepedia

Phenotyping Assays

Phenotyping Assay is a biochemical method that quantifies the in vivo activity of specific cytochrome P450 enzymes by measuring the metabolic ratio of a probe drug and its metabolite to assess an individual's drug-metabolizing phenotype.

72

Publications

3.4K

Citations

419

Authors

168

Institutions

Publications per year

2017–2026

12

Variants

Phenotyping Assay

Parents

Publications

72

Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility

Shan Zhong, A. Forbes Howie, B Ketterer et al. · Carcinogenesis · 1991 · 271 citations

, , +10

A New Automated Method for Phenotyping Arylesterase (EC 3.1.1.2) Based Upon Inhibition of Enzymatic Hydrolysis of 4-Nitrophenyl Acetate by Phenyl Acetate

L. Haagen, A. Brock · Clinical Chemistry and Laboratory Medicine (CCLM) · 1992 · 248 citations · Full text

, , +15

The karolinska cocktail for phenotyping of five human cytochrome P450 enzymes

Michael L. Christensen · Clinical Pharmacology & Therapeutics · 2003 · 157 citations

, , +16

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N -acetyltransferase-2, and xanthine oxidase with the ″Cooperstown cocktail”

Daniel S. Streetman · Clinical Pharmacology & Therapeutics · 2000 · 143 citations

, , +14

Phenomics for photosynthesis, growth and reflectance in Arabidopsis thaliana reveals circadian and long-term fluctuations in heritability

Pádraic J. Flood, Willem Kruijer, Sabine Schnabel et al. · Plant Methods · 2016 · 140 citations · Full text

, , +14

1–5 of 72

Authors

419

  1. RK
    Robert Kulawy

    Albany Research Institute, United States

    3 publications · 137 citations

    3

    h-index

  2. JB
    Joseph Bertino

    Bassett Healthcare Network, United States

    3 publications · 137 citations

    3

    h-index

  3. MH
    Manuel Haschke

    University Hospital of Basel, Switzerland

    3 publications · 123 citations

    3

    h-index

  4. UF
    Uwe Fuhr

    University of Cologne, Germany

    3 publications · 229 citations

    3

    h-index

  5. YD
    Youssef Daali

    University Hospital of Geneva, Switzerland

    3 publications · 141 citations

    3

    h-index

1–5 of 419

Institutions

168

  1. University of Basel

    Basel, Switzerland

    5 h-index

    25 publications

    867 citations

  2. Bassett Healthcare Network

    Cooperstown, United States

    4 h-index

    6 publications

    382 citations

  3. University of Southern Denmark

    Odense, Denmark

    4 h-index

    8 publications

    169 citations

  4. University Hospital of Geneva

    Geneva, Switzerland

    3 h-index

    14 publications

    635 citations

  5. University Hospital of Basel

    Basel, Switzerland

    3 h-index

    12 publications

    290 citations

  6. University of Cologne

    Cologne, Germany

    3 h-index

    16 publications

    1.2K citations

  7. Odense University Hospital

    Odense, Denmark

    2 h-index

    3 publications

    89 citations

  8. Yale University

    New Haven, United States

    2 h-index

    4 publications

    87 citations

1–8 of 168

Venues

  1. British Journal of Clinical Pharmacology

    BJCP · 6 publications · 147 citations

    6

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 6 publications · 602 citations

    6

    h-index

  3. European Journal of Clinical Pharmacology

    5 publications · 263 citations

    5

    h-index

  4. Basic & Clinical Pharmacology & Toxicology

    BCPT · 4 publications · 120 citations

    4

    h-index

  5. Drug Metabolism and Disposition

    3 publications · 109 citations

    3

    h-index

1–5