Concepedia

Pharmacodynamic Breakpoints

Pharmacodynamic Breakpoints is a pharmacological metric that defines the threshold concentration of an antimicrobial agent at which a pathogen's growth is effectively inhibited, distinguishing it from other susceptibility classifications by linking drug exposure dynamics to microbial response outcomes.

59

Publications

3.1K

Citations

284

Authors

179

Institutions

Publications per year

2017–2026

22

Parents

Publications

59

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

Paul G. Ambrose, Sujata M. Bhavnani, Christopher M. Rubino et al. · Clinical Infectious Diseases · 2006 · 700 citations · Full text

, , +17

Pharmacodynamics of Fluoroquinolones against <i>Streptococcus pneumoniae</i> in Patients with Community-Acquired Respiratory Tract Infections

Paul G. Ambrose, Dennis M. Grasela, Thaddeus H. Grasela et al. · Antimicrobial Agents and Chemotherapy · 2001 · 298 citations · Full text

, , +16

EUCAST technical note on isavuconazole breakpoints for Aspergillus, itraconazole breakpoints for Candida and updates for the antifungal susceptibility testing method documents

Maiken Cavling Arendrup, Cecilie Torp Andersen, Paul E. Verweij · Clinical Microbiology and Infection · 2016 · 133 citations · Full text

, , +17

Challenging a dogma: antimicrobial susceptibility testing breakpoints for Mycobacterium tuberculosis

Kristian Ängeby, Pontus Juréen, Gunnar Kahlmeter et al. · Bulletin of the World Health Organization · 2012 · 103 citations · Full text

, , +16

Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation

Christopher R. Frei, Nathan P. Wiederhold, David S. Burgess · Journal of Antimicrobial Chemotherapy · 2008 · 103 citations · Full text

, , +16

1–5 of 59

Authors

284

  1. CL
    Christopher Longshaw

    Astellas Pharma (United Kingdom), United Kingdom

    5 publications · 132 citations

    5

    h-index

  2. AS
    Anne Santerre Henriksen

    Leo Pharma (Denmark), Denmark

    4 publications · 97 citations

    4

    h-index

  3. PG
    Paul G. Ambrose

    Institute for Clinical Pharmacodynamics (United States), United States

    4 publications · 1.1K citations

    4

    h-index

  4. TG
    Tawanda Gumbo

    Baylor University Medical Center, United States

    3 publications · 796 citations

    3

    h-index

  5. JL
    Joseph L. Kuti

    Hartford Hospital, United States

    3 publications · 176 citations

    3

    h-index

1–5 of 284

Institutions

179

  1. Royal Veterinary College

    London, United Kingdom

    3 h-index

    10 publications

    258 citations

  2. École Nationale Vétérinaire de Toulouse

    Toulouse, France

    3 h-index

    10 publications

    168 citations

  3. Inserm

    Paris, France

    3 h-index

    7 publications

    194 citations

  4. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    3 h-index

    9 publications

    599 citations

  5. CNR de la Résistance aux Antibiotiques

    Besançon, France

    3 h-index

    5 publications

    154 citations

  6. Ollscoil na Gaillimhe – University of Galway

    Galway, Ireland

    3 h-index

    4 publications

    80 citations

  7. Cognizant (United States)

    Teaneck, United States

    3 h-index

    8 publications

    1.1K citations

  8. Albany Research Institute

    Albany, United States

    3 h-index

    5 publications

    187 citations

1–8 of 179

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 11 publications · 751 citations

    11

    h-index

  2. Journal of Antimicrobial Chemotherapy

    JAC · 7 publications · 361 citations

    7

    h-index

  3. Clinical Infectious Diseases

    CID · 5 publications · 893 citations

    5

    h-index

  4. Journal of Global Antimicrobial Resistance

    4 publications · 90 citations

    4

    h-index

  5. Aquaculture

    3 publications · 65 citations

    3

    h-index

1–5