Concepedia

Phagophore Formation

Phagophore Formation is a cellular process in the context of autophagy characterized by the de novo assembly and expansion of a cup-shaped double-membrane structure, the phagophore, from specific nucleation sites such as the endoplasmic reticulum, which serves as the precursor to the autophagosome and distinguishes itself from other membrane biogenesis events by its unique initiation through autophagy-related (ATG) protein machinery and its selective engulfment of cytoplasmic cargo.

186

Publications

17.9K

Citations

870

Authors

333

Institutions

Publications per year

2017–2026

92

Parents

Publications

186

Atg8 Controls Phagophore Expansion during Autophagosome Formation

Zhiping Xie, Usha Nair, Daniel J. Klionsky · Molecular Biology of the Cell · 2008 · 758 citations · Full text

, , +9

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

Hannah E.J. Polson, Jane De Lartigue, Daniel J. Rigden et al. · Autophagy · 2010 · 685 citations · Full text

, , +11

3D tomography reveals connections between the phagophore and endoplasmic reticulum

Päivi Ylä‐Anttila, Helena Vihinen, Eija Jokitalo et al. · Autophagy · 2009 · 645 citations

, , +17

Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy

Andrea Orsi, Minoo Razi, Hannah C. Dooley et al. · Molecular Biology of the Cell · 2012 · 570 citations

, , +13

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

Muriel Mari, Janice Griffith, Ester Rieter et al. · The Journal of Cell Biology · 2010 · 484 citations · Full text

, , +12

1–5 of 186

Authors

870

  1. DJ
    Daniel J. Klionsky

    University of Michigan, United States

    29 publications · 3.8K citations

    25

    h-index

  2. UN
    Usha Nair

    University of Michigan, United States

    12 publications · 2.2K citations

    12

    h-index

  3. FR
    Fulvio Reggiori

    University Medical Center Utrecht, Netherlands

    11 publications · 1.5K citations

    11

    h-index

  4. MB
    Misuzu Baba

    Japan Women's University, Japan

    7 publications · 796 citations

    7

    h-index

  5. JH
    James H. Hurley

    National Institutes of Health, United States

    7 publications · 268 citations

    7

    h-index

1–5 of 870

Institutions

333

  1. University of Michigan

    Ann Arbor, United States

    25 h-index

    84 publications

    11K citations

  2. University of California, Berkeley

    Berkeley, United States

    9 h-index

    34 publications

    3.3K citations

  3. University Medical Center Utrecht

    Utrecht, The Netherlands

    8 h-index

    22 publications

    4.8K citations

  4. Ann Arbor Center for Independent Living

    Ann Arbor, United States

    7 h-index

    16 publications

    1.9K citations

  5. QB3

    San Francisco, United States

    7 h-index

    28 publications

    1.2K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    25 publications

    3.8K citations

  7. University of California San Diego

    San Diego, United States

    7 h-index

    22 publications

    1.9K citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    6 h-index

    7 publications

    227 citations

1–8 of 333

Venues

  1. Autophagy

    78 publications · 6.6K citations

    40

    h-index

  2. The Journal of Cell Biology

    JCB · 12 publications · 1.8K citations

    12

    h-index

  3. Nature Communications

    10 publications · 1.4K citations

    10

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1.3K citations

    9

    h-index

  5. Molecular Biology of the Cell

    MBC · 9 publications · 2.5K citations

    9

    h-index

1–5