Concepedia

Ph-rate Profiles

pH-Rate Profiles is a systematic representation of the dependence of an enzyme-catalyzed reaction rate on solution pH, serving as a kinetic framework to elucidate the ionization states of active site residues critical to the catalytic mechanism.

502

Publications

21.8K

Citations

1.5K

Authors

419

Institutions

Publications per year

2017–2026

34

Parents

Publications

502

The Catalytic Mechanism of Carbonic Anhydrase. Hydrogen-Isotope Effects on the Kinetic Parameters of the Human C Isoenzyme

Håkan Steiner, Bengt‐Harald Jonsson, Sven Lindskog · European Journal of Biochemistry · 1975 · 423 citations · Full text

, , +16

Protodeboronation of Heteroaromatic, Vinyl, and Cyclopropyl Boronic Acids: pH–Rate Profiles, Autocatalysis, and Disproportionation

Paul Alan Cox, Andrew G. Leach, Andrew D. Campbell et al. · Journal of the American Chemical Society · 2016 · 371 citations · Full text

, , +14

Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.

Harald Otto, T Marti, M. Holz et al. · Proceedings of the National Academy of Sciences · 1989 · 319 citations · Full text

, , +13

Mechanism for the Hydrolysis of Organophosphates by the Bacterial Phosphotriesterase

Sarah D. Aubert, Yingchun Li, Frank M. Raushel · Biochemistry · 2004 · 315 citations

, , +14

Base-Catalyzed Aryl-B(OH)<sub>2</sub> Protodeboronation Revisited: From Concerted Proton Transfer to Liberation of a Transient Aryl Anion

Paul Alan Cox, Marc Reid, Andrew G. Leach et al. · Journal of the American Chemical Society · 2017 · 312 citations · Full text

, , +15

1–5 of 502

Authors

1.5K

  1. LP
    László Polgár

    Hungarian Academy of Sciences, Hungary

    9 publications · 435 citations

    9

    h-index

  2. RS
    R. S. Brown

    Queen's University, Canada

    9 publications · 255 citations

    9

    h-index

  3. DS
    Diógenes Santiago Santos

    Pontifícia Universidade Católica do Rio Grande do Sul, Brazil

    8 publications · 179 citations

    8

    h-index

  4. LA
    Luiz Augusto Basso

    Pontifícia Universidade Católica do Rio Grande do Sul, Brazil

    8 publications · 179 citations

    8

    h-index

  5. JG
    José G. Santos

    Pontificia Universidad Católica de Chile, Chile

    7 publications · 228 citations

    7

    h-index

1–5 of 1.5K

Institutions

419

  1. Institute of Molecular Life Sciences

    Budapest, Hungary

    9 h-index

    19 publications

    723 citations

  2. Pontifícia Universidade Católica do Rio Grande do Sul

    Porto Alegre, Brazil

    8 h-index

    39 publications

    868 citations

  3. Pennsylvania State University

    State College, United States

    8 h-index

    18 publications

    575 citations

  4. Hungarian Academy of Sciences

    Budapest, Hungary

    8 h-index

    18 publications

    663 citations

  5. University of Florida

    Gainesville, United States

    7 h-index

    17 publications

    1K citations

  6. Queen's University

    Kingston, Canada

    7 h-index

    21 publications

    555 citations

  7. Pontificia Universidad Católica de Chile

    Santiago, Chile

    7 h-index

    23 publications

    747 citations

  8. University of Michigan

    Ann Arbor, United States

    6 h-index

    16 publications

    907 citations

1–8 of 419

Venues

  1. Biochemistry

    64 publications · 3.5K citations

    35

    h-index

  2. Journal of Biological Chemistry

    JBC · 47 publications · 2.3K citations

    32

    h-index

  3. Journal of the American Chemical Society

    JACS · 33 publications · 2.5K citations

    24

    h-index

  4. European Journal of Biochemistry

    EJB · 18 publications · 1.4K citations

    17

    h-index

  5. 17

    h-index

1–5