Concepedia

Ph-dependent Irritation

pH-Dependent Irritation is a mucosal irritation response distinguished by its direct modulation by the acidity or alkalinity of the local microenvironment, typically occurring when deviations from physiological pH levels disrupt mucosal barrier integrity or activate pH-sensitive nociceptive pathways.

44

Publications

1.9K

Citations

152

Authors

60

Institutions

Publications per year

2017–2026

2

Parents

Publications

44

A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro

Steen Kh, AE Steen · Journal of Neuroscience · 1995 · 294 citations · Full text

, , +17

Evaluation of pH changes in inflammation of the subcutaneous air pouch lining in the rat, induced by carrageenan, dextran and staphylococcus aureus

A. Punnia‐Moorthy · Journal of Oral Pathology and Medicine · 1987 · 134 citations

, , +12

A TRPA1-dependent mechanism for the pungent sensation of weak acids

Yuanyuan Y. Wang, Rui B. Chang, Sallie D. Allgood et al. · The Journal of General Physiology · 2011 · 134 citations · Full text

, , +17

Faecal enzymes: in vivo human skin irritation

Pia Haubro Andersen, A. P. Bucher, Isra Saeed et al. · Contact Dermatitis · 1994 · 129 citations

, , +14

Correlation between pH and irritant effect of cleansers marketed for dry skin

Lourdes Baranda, Roberto González‐Amaro, Bertha Torres‐Álvarez et al. · International Journal of Dermatology · 2002 · 125 citations

, , +13

1–5 of 44

Authors

152

  1. SS
    Swarnjit Singh

    University of Alabama at Birmingham, United States

    1 publications · 13 citations

    1

    h-index

  2. PL
    Peter Lersch

    Evonik (Germany), Germany

    1 publications · 16 citations

    1

    h-index

  3. DJ
    David J. Schaeffer

    University of Illinois Urbana-Champaign, United States

    1 publications · 12 citations

    1

    h-index

  4. GB
    G.W. Bierbower

    United States Food and Drug Administration, United States

    1 publications · 46 citations

    1

    h-index

  5. MH
    M.J. How

    Unilever (United Kingdom), United Kingdom

    1 publications · 47 citations

    1

    h-index

1–5 of 152

Institutions

60

  1. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    3 h-index

    4 publications

    667 citations

  2. Novartis (Switzerland)

    Basel, Switzerland

    2 h-index

    4 publications

    136 citations

  3. University of California, San Francisco

    San Francisco, United States

    2 h-index

    6 publications

    495 citations

  4. Korea University

    Seoul, South Korea

    1 h-index

    2 publications

    88 citations

  5. Wake Forest University

    Winston-Salem, United States

    1 h-index

    2 publications

    268 citations

  6. Walter Reed National Military Medical Center

    Bethesda, United States

    1 h-index

    4 publications

    48 citations

  7. Osnabrück University

    Osnabrück, Germany

    1 h-index

    1 publications

    28 citations

  8. MZA Associates (United States)

    Albuquerque, United States

    1 h-index

    6 publications

    102 citations

1–8 of 60

Venues

  1. PubMed

    Repository · 4 publications · 84 citations

    4

    h-index

  2. Journal of Pharmaceutical Sciences

    3 publications · 87 citations

    3

    h-index

  3. International Journal of Cosmetic Science

    3 publications · 138 citations

    3

    h-index

  4. Toxicology

    1 publications · 46 citations

    1

    h-index

  5. Digestive Diseases and Sciences

    1 publications · 13 citations

    1

    h-index

1–5