Concepedia

Ph Domains

PH Domain is a type of protein structural domain that belongs to the superfamily of modular protein domains and is specifically characterized by its ability to bind phosphoinositide lipids, thereby mediating intracellular signaling and membrane targeting events.

693

Publications

54.6K

Citations

3.4K

Authors

834

Institutions

Publications per year

2017–2026

97

Parents

Publications

693

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

, , +17

Visualization of Phosphoinositides That Bind Pleckstrin Homology Domains: Calcium- and Agonist-induced Dynamic Changes and Relationship to Myo-[3H]inositol-labeled Phosphoinositide Pools

Péter Várnai, Tamás Balla · The Journal of Cell Biology · 1998 · 864 citations · Full text

, , +17

The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System

Marie‐Louise Bang, Thomas Centner, Friderike Fornoff et al. · Circulation Research · 2001 · 716 citations

, , +12

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

Mark A. Lemmon, Kathryn M. Ferguson · Biochemical Journal · 2000 · 708 citations · Full text

, , +17

G Protein Signaling Events Are Activated at the Leading Edge of Chemotactic Cells

Carole A. Parent, Brenda J. Blacklock, Wendy Froehlich et al. · Cell · 1998 · 623 citations · Full text

, , +17

1–5 of 693

Authors

3.4K

  1. MA
    Mark A. Lemmon

    University of Pennsylvania, United States

    21 publications · 4.2K citations

    20

    h-index

  2. CP
    C. Peter Downes

    University of Dundee, United Kingdom

    12 publications · 2.1K citations

    12

    h-index

  3. TB
    Tamás Balla

    National Institutes of Health, United States

    11 publications · 2.3K citations

    11

    h-index

  4. DR
    Dario R. Alessi

    MRC Protein Phosphorylation and Ubiquitylation Unit, United Kingdom

    11 publications · 2K citations

    11

    h-index

  5. PA
    Paul A. Randazzo

    National Cancer Institute, United States

    10 publications · 422 citations

    10

    h-index

1–5 of 3.4K

Institutions

834

  1. National Institutes of Health

    Bethesda, United States

    27 h-index

    39 publications

    3.6K citations

  2. Harvard University

    Cambridge, United States

    26 h-index

    26 publications

    2.9K citations

  3. University of Dundee

    Dundee, United Kingdom

    24 h-index

    26 publications

    3.5K citations

  4. University of Pennsylvania

    Philadelphia, United States

    22 h-index

    24 publications

    2.2K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    19 h-index

    20 publications

    1.3K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    22 publications

    1.2K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    17 publications

    2.7K citations

  8. The University of Tokyo

    Tokyo, Japan

    15 h-index

    16 publications

    1.2K citations

1–8 of 834

Venues

  1. Journal of Biological Chemistry

    JBC · 130 publications · 12.5K citations

    64

    h-index

  2. Biochemical Journal

    BJ · 38 publications · 5.4K citations

    32

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 33 publications · 4.1K citations

    32

    h-index

  4. Biochemistry

    32 publications · 1.6K citations

    25

    h-index

  5. Molecular and Cellular Biology

    MCB · 25 publications · 2.8K citations

    24

    h-index

1–5