Concepedia

Persistent Inflammatory Signaling

Persistent Inflammatory Signaling is a pathophysiological mechanism characterized by the sustained activation of immune signaling pathways in the wound microenvironment, distinguished from acute inflammatory responses by its failure to resolve and its contribution to tissue damage and impaired healing in chronic wounds.

70

Publications

4.1K

Citations

471

Authors

189

Institutions

Publications per year

2017–2026

21

Parents

Publications

70

Blocking Interleukin-1β Induces a Healing-Associated Wound Macrophage Phenotype and Improves Healing in Type 2 Diabetes

Rita E. Mirza, Milie M. Fang, William J. Ennis et al. · Diabetes · 2013 · 441 citations · Full text

, , +17

Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice

Rita E. Mirza, Milie M. Fang, Eileen M Weinheimer-Haus et al. · Diabetes · 2013 · 319 citations · Full text

, , +17

Differential Proteomic Analysis Distinguishes Tissue Repair Biomarker Signatures in Wound Exudates Obtained from Normal Healing and Chronic Wounds

Sabine A. Eming, Manuel Koch, Andreas Krieger et al. · Journal of Proteome Research · 2010 · 247 citations

, , +17

ISSLS Prize Winner: Repeated Disc Injury Causes Persistent Inflammation

J. Ulrich, Ellen Liebenberg, Daniel Thuillier et al. · Spine · 2007 · 192 citations

, , +17

Persistent Inflammation Induces GluR2 Internalization via NMDA Receptor-Triggered PKC Activation in Dorsal Horn Neurons

Jang-Su Park, Nana Voitenko, Ronald S. Petralia et al. · Journal of Neuroscience · 2009 · 168 citations · Full text

, , +17

1–5 of 70

Authors

471

  1. MM
    Milie M. Fang

    University of Illinois Chicago, United States

    2 publications · 760 citations

    2

    h-index

  2. RK
    Rohini Kuner

    Heidelberg University, Germany

    2 publications · 166 citations

    2

    h-index

  3. JΒ
    João Β. Calixto

    Universidade Federal de Santa Catarina, Brazil

    2 publications · 113 citations

    2

    h-index

  4. MZ
    Min Zhuo

    University of Toronto, Canada

    2 publications · 103 citations

    2

    h-index

  5. RE
    Rita E. Mirza

    University of Illinois Chicago, United States

    2 publications · 760 citations

    2

    h-index

1–5 of 471

Institutions

189

  1. University of Florida

    Gainesville, United States

    3 h-index

    17 publications

    1.3K citations

  2. Universidade Federal de Santa Catarina

    Florianópolis, Brazil

    3 h-index

    14 publications

    836 citations

  3. University of Iowa

    Iowa City, United States

    3 h-index

    5 publications

    142 citations

  4. Boston University

    Boston, United States

    2 h-index

    8 publications

    632 citations

  5. University College London

    London, United Kingdom

    2 h-index

    6 publications

    165 citations

  6. University of Illinois Chicago

    Chicago, United States

    2 h-index

    9 publications

    3.4K citations

  7. Georgia State University

    Atlanta, United States

    2 h-index

    3 publications

    55 citations

  8. Heidelberg University

    Heidelberg, Germany

    2 h-index

    10 publications

    1K citations

1–8 of 189

Venues

  1. The Journal of Immunology

    JI · 4 publications · 204 citations

    4

    h-index

  2. PubMed

    Repository · 3 publications · 100 citations

    3

    h-index

  3. Brain Research

    2 publications · 91 citations

    2

    h-index

  4. Journal of Neuroscience

    2 publications · 254 citations

    2

    h-index

  5. Diabetes

    2 publications · 760 citations

    2

    h-index

1–5