Concepedia

Peroxisome Proliferation

Peroxisome Proliferation is a biological process characterized by the increase in peroxisome number within a cell, driven by the activation of specific nuclear receptors and associated gene expression programs that enhance peroxisomal biogenesis and metabolic function.

581

Publications

40.6K

Citations

1.9K

Authors

502

Institutions

Publications per year

2017–2026

24

Parents

Publications

581

Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators

Susanna S.T. Lee, Thierry Pineau, John Drago et al. · Molecular and Cellular Biology · 1995 · 1.6K citations · Full text

, , +16

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

Paul B. Lazarow, C. De Duve · Proceedings of the National Academy of Sciences · 1976 · 1.1K citations · Full text

, , +17

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

Janardan K. Reddy, Daniel L. Azarnoff, Charles E. Hignite · Nature · 1980 · 844 citations

, , +16

PPAR  and human metabolic disease

Robert K. Semple · Journal of Clinical Investigation · 2006 · 821 citations · Full text

, , +17

Differential Activation of Nuclear Receptors by Perfluorinated Fatty Acid Analogs and Natural Fatty Acids: A Comparison of Human, Mouse, and Rat Peroxisome Proliferator-Activated Receptor-α, -β, and -γ, Liver X Receptor-β, and Retinoid X Receptor-α

John P. Vanden Heuvel, Jerry T. Thompson, Steven R. Frame et al. · Toxicological Sciences · 2006 · 473 citations · Full text

, , +13

1–5 of 581

Authors

1.9K

  1. JK
    Janardan K. Reddy

    Northwestern University, United States

    63 publications · 5.8K citations

    37

    h-index

  2. MS
    Mahendra S. Rao

    National Institute on Aging, United States

    22 publications · 1.8K citations

    19

    h-index

  3. ND
    Narendra D. Lalwani

    Northwestern University, United States

    19 publications · 1.5K citations

    17

    h-index

  4. MK
    M. K. Reddy

    International Centre for Genetic Engineering and Biotechnology, India

    17 publications · 1.3K citations

    16

    h-index

  5. JW
    Joseph W. DePierre

    Stockholm University, Sweden

    19 publications · 803 citations

    16

    h-index

1–5 of 1.9K

Institutions

502

  1. Northwestern University

    Evanston, United States

    37 h-index

    255 publications

    23.2K citations

  2. Research Triangle Park Foundation

    Durham, United States

    20 h-index

    65 publications

    4.1K citations

  3. Stockholm University

    Stockholm, Sweden

    16 h-index

    61 publications

    2.7K citations

  4. Heidelberg University

    Heidelberg, Germany

    16 h-index

    60 publications

    4K citations

  5. University of Groningen

    Groningen, The Netherlands

    14 h-index

    69 publications

    4.7K citations

  6. National Institutes of Health

    Bethesda, United States

    14 h-index

    69 publications

    20.9K citations

  7. National Institute of Environmental Health Sciences

    Durham, United States

    12 h-index

    35 publications

    1.9K citations

  8. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    12 h-index

    28 publications

    1.7K citations

1–8 of 502

Venues

  1. Carcinogenesis

    40 publications · 2.2K citations

    30

    h-index

  2. Journal of Biological Chemistry

    JBC · 28 publications · 3.4K citations

    27

    h-index

  3. PubMed

    Repository · 35 publications · 2.6K citations

    24

    h-index

  4. Toxicological Sciences

    29 publications · 2.5K citations

    24

    h-index

  5. Toxicology and Applied Pharmacology

    TAAP · 22 publications · 1.4K citations

    18

    h-index

1–5