Concepedia

Peroxiredoxin Hyperoxidation

Peroxiredoxin Hyperoxidation is a biochemical process in which the catalytic cysteine residue of a peroxiredoxin enzyme undergoes irreversible oxidation to sulfinic or sulfonic acid forms, thereby inactivating its peroxidase function and potentially serving a regulatory role in cellular redox signaling.

59

Publications

4.7K

Citations

323

Authors

104

Institutions

Publications per year

2017–2026

20

Parents

Publications

59

Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid

Kap‐Seok Yang, Sang Won Kang, Hyun Ae Woo et al. · Journal of Biological Chemistry · 2002 · 455 citations · Full text

, , +17

Characterization of Mammalian Sulfiredoxin and Its Reactivation of Hyperoxidized Peroxiredoxin through Reduction of Cysteine Sulfinic Acid in the Active Site to Cysteine

Tong‐Shin Chang, Woojin Jeong, Hyun Ae Woo et al. · Journal of Biological Chemistry · 2004 · 384 citations · Full text

, , +16

Oxidative Stress-dependent Structural and Functional Switching of a Human 2-Cys Peroxiredoxin Isotype II That Enhances HeLa Cell Resistance to H2O2-induced Cell Death

Jeong Chan Moon, Young‐Sool Hah, Woe Yeon Kim et al. · Journal of Biological Chemistry · 2005 · 300 citations · Full text

, , +17

Inactivation of a Peroxiredoxin by Hydrogen Peroxide Is Critical for Thioredoxin-Mediated Repair of Oxidized Proteins and Cell Survival

Alison M. Day, Jonathon D. Brown, Sarah R. Taylor et al. · Molecular Cell · 2012 · 211 citations · Full text

, , +17

Irreversible Oxidation of the Active-site Cysteine of Peroxiredoxin to Cysteine Sulfonic Acid for Enhanced Molecular Chaperone Activity

Jung Chae Lim, Hoon‐In Choi, Yu Sun Park et al. · Journal of Biological Chemistry · 2008 · 179 citations · Full text

, , +14

1–5 of 59

Authors

323

  1. SG
    Sue Goo Rhee

    National Heart Lung and Blood Institute, United States

    11 publications · 1.7K citations

    11

    h-index

  2. HA
    Hyun Ae Woo

    Ewha Womans University, South Korea

    8 publications · 1.5K citations

    8

    h-index

  3. CC
    Christine C. Winterbourn

    Christchurch Clinical Studies Trust, New Zealand

    6 publications · 420 citations

    6

    h-index

  4. WT
    W. Todd Lowther

    Wake Forest University, United States

    5 publications · 303 citations

    5

    h-index

  5. CM
    Cristina M. Furdui

    Wake Forest University, United States

    5 publications · 324 citations

    5

    h-index

1–5 of 323

Institutions

104

  1. Ewha Womans University

    Seoul, South Korea

    10 h-index

    54 publications

    5K citations

  2. Wake Forest University

    Winston-Salem, United States

    8 h-index

    37 publications

    2.3K citations

  3. University of Otago

    Dunedin, New Zealand

    6 h-index

    29 publications

    2.3K citations

  4. University of Vermont

    Burlington, United States

    4 h-index

    14 publications

    934 citations

  5. National Institutes of Health

    Bethesda, United States

    4 h-index

    22 publications

    5.1K citations

  6. National Heart Lung and Blood Institute

    Bethesda, United States

    4 h-index

    21 publications

    4.7K citations

  7. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    4 h-index

    9 publications

    338 citations

  8. University of Kaiserslautern

    Kaiserslautern, Germany

    3 h-index

    13 publications

    499 citations

1–8 of 104

Venues

  1. Journal of Biological Chemistry

    JBC · 16 publications · 2.2K citations

    16

    h-index

  2. Antioxidants and Redox Signaling

    ARS · 5 publications · 354 citations

    5

    h-index

  3. Free Radical Biology and Medicine

    3 publications · 105 citations

    3

    h-index

  4. Redox Biology

    3 publications · 85 citations

    3

    h-index

  5. Biochemical Journal

    BJ · 3 publications · 200 citations

    3

    h-index

1–5