Concepedia

Peptide Aggregation

Peptide Aggregation is the process by which individual peptide molecules associate through non-covalent interactions, such as hydrogen bonding and hydrophobic effects, to form ordered or disordered supramolecular assemblies, often leading to the formation of amyloid fibrils or amorphous aggregates implicated in neurodegenerative diseases and protein misfolding disorders.

1.3K

Publications

81.9K

Citations

5.3K

Authors

1.4K

Institutions

Publications per year

2017–2026

414

Parents

Publications

1.3K

Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability

Karie N. Dahlgren, Arlene M. Manelli, W. Blaine Stine et al. · Journal of Biological Chemistry · 2002 · 1.4K citations · Full text

, , +17

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

Daniel Burdick, AJ Walencewicz, CG Glabe et al. · Journal of Neuroscience · 1993 · 1.4K citations · Full text

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Rationalization of the effects of mutations on peptide andprotein aggregation rates

Fabrizio Chiti, Massimo Stefani, Niccolò Taddei et al. · Nature · 2003 · 1.1K citations

, , +12

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

Debra Burdick, Brian Soreghan, Min‐Sung Kwon et al. · Journal of Biological Chemistry · 1992 · 998 citations · Full text

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In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

Christian J. Pike, Andrea J. Walencewicz, Charles Glabe et al. · Brain Research · 1991 · 827 citations

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1–5 of 1.3K

Authors

5.3K

  1. AG
    Astrid Gräslund

    Stockholm University, Sweden

    20 publications · 1.2K citations

    19

    h-index

  2. GW
    Guanghong Wei

    Fudan University, China

    24 publications · 1.2K citations

    19

    h-index

  3. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    18 publications · 3.4K citations

    18

    h-index

  4. JS
    Joan‐Emma Shea

    University of California, Santa Barbara, United States

    15 publications · 1.2K citations

    15

    h-index

  5. TP
    Tuomas P. J. Knowles

    University of Cambridge, United Kingdom

    15 publications · 1.7K citations

    15

    h-index

1–5 of 5.3K

Institutions

1.4K

  1. University of Cambridge

    Cambridge, United Kingdom

    30 h-index

    163 publications

    18.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    29 h-index

    156 publications

    8K citations

  3. Fudan University

    Shanghai, China

    21 h-index

    99 publications

    4.7K citations

  4. Lund University

    Lund, Sweden

    21 h-index

    71 publications

    7.2K citations

  5. Stockholm University

    Stockholm, Sweden

    20 h-index

    102 publications

    5.7K citations

  6. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    18 h-index

    66 publications

    3.6K citations

  7. Sorbonne Université

    Paris, France

    18 h-index

    46 publications

    2K citations

  8. University of California, Santa Barbara

    Santa Barbara, United States

    18 h-index

    72 publications

    4.2K citations

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Venues

  1. Journal of the American Chemical Society

    JACS · 38 publications · 3.7K citations

    33

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  2. The Journal of Physical Chemistry B

    72 publications · 2.9K citations

    33

    h-index

  3. Biochemistry

    42 publications · 3.2K citations

    32

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 30 publications · 6K citations

    30

    h-index

  5. Journal of Biological Chemistry

    JBC · 35 publications · 6K citations

    30

    h-index

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