Concepedia

Pdz Domains

PDZ Domain is a structural domain in proteins that serves as a protein interaction module by specifically recognizing and binding to short peptide sequences, typically at the C-termini of target proteins, thereby mediating the assembly of multi-protein complexes involved in cellular signaling and organization.

1.6K

Publications

137.4K

Citations

6.8K

Authors

1.4K

Institutions

Publications per year

2017–2026

179

Parents

Publications

1.6K

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

Hans‐Christian Kornau, Leslie T. Schenker, Mary B. Kennedy et al. · Science · 1995 · 1.9K citations

, , +14

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

Jay E. Brenman, Daniel S. Chao, Stephen Gee et al. · Cell · 1996 · 1.6K citations · Full text

, , +14

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

Zhou Songyang, A. S. Fanning, Chenglai Fu et al. · Science · 1997 · 1.4K citations

, , +17

Evolutionarily Conserved Pathways of Energetic Connectivity in Protein Families

Steve W. Lockless, Rama Ranganathan · Science · 1999 · 1.3K citations

, , +16

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

D. Doyle, Alice A. Lee, John H. Lewis et al. · Cell · 1996 · 1.1K citations · Full text

, , +16

1–5 of 1.6K

Authors

6.8K

  1. MZ
    Mingjie Zhang

    Hong Kong University of Science and Technology, Hong Kong SAR China

    25 publications · 1.9K citations

    21

    h-index

  2. SG
    Stefano Gianni

    Istituto Pasteur, Italy

    29 publications · 1.1K citations

    20

    h-index

  3. PJ
    Per Jemth

    Uppsala University, Sweden

    30 publications · 1.1K citations

    19

    h-index

  4. RA
    Randy A. Hall

    Emory University, United States

    19 publications · 1.8K citations

    18

    h-index

  5. DS
    David S. Bredt

    University of California, San Francisco, United States

    18 publications · 5.1K citations

    18

    h-index

1–5 of 6.8K

Institutions

1.4K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    70 h-index

    258 publications

    76K citations

  2. Johns Hopkins University

    Baltimore, United States

    47 h-index

    264 publications

    45.5K citations

  3. Harvard University

    Cambridge, United States

    44 h-index

    207 publications

    38.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    42 h-index

    431 publications

    25.2K citations

  5. University of California, San Francisco

    San Francisco, United States

    37 h-index

    134 publications

    30.9K citations

  6. Johns Hopkins Medicine

    Baltimore, United States

    34 h-index

    181 publications

    25.6K citations

  7. Inserm

    Paris, France

    34 h-index

    215 publications

    17K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    30 h-index

    96 publications

    17.5K citations

1–8 of 1.4K

Venues

  1. Journal of Biological Chemistry

    JBC · 284 publications · 27.1K citations

    98

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 62 publications · 10.1K citations

    52

    h-index

  3. Journal of Neuroscience

    48 publications · 6.4K citations

    43

    h-index

  4. The Journal of Cell Biology

    JCB · 37 publications · 9.1K citations

    37

    h-index

  5. FEBS Letters

    38 publications · 2.7K citations

    29

    h-index

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