Concepedia

Pathway Sensitivity Analysis

Pathway Sensitivity Analysis is a computational method used in metabolic pathway analysis that systematically quantifies the responsiveness of pathway outputs to variations in enzyme activities, metabolite concentrations, or kinetic parameters, thereby distinguishing it from other analyses by its focus on perturbation-based assessment of metabolic control and robustness.

13

Publications

610

Citations

57

Authors

42

Institutions

Publications per year

2017–2026

3

Variants

Metabolic Pathway Sensitivity Analysis

Parents

Publications

13

Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κ B Signal Transduction Pathway

Kwang‐Hyun Cho, Sung‐Young Shin, Walter Kölch et al. · SIMULATION · 2003 · 173 citations

, , +13

Sensitivity analysis for the reduction of complex metabolism models

Daniela Degenring, C. Froemel, Gerhard Dikta et al. · Journal of Process Control · 2004 · 133 citations

, , +13

A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes

Jun Liu, Jan B. van Klinken, Sabina Semiz et al. · Diabetes · 2017 · 54 citations · Full text

, , +16

Sensitivity of a Near-Equilibrium Reaction in a Metabolic Pathway to Changes in Substrate Concentration

Bernard Crabtree, Eric A. Newsholme · European Journal of Biochemistry · 1978 · 52 citations

, , +16

A multi-omics concentration-response framework uncovers novel understanding of triclosan effects in the chlorophyte Scenedesmus vacuolatus

Floriane Larras, Élise Billoir, Stefan Scholz et al. · Journal of Hazardous Materials · 2020 · 39 citations · Full text

, , +16

1–5 of 13

Authors

57

  1. AG
    Anna Gambin

    University of Warsaw, Poland

    1 publications · 19 citations

    1

    h-index

  2. TS
    Thomas S. Deisboeck

    Massachusetts General Hospital, United States

    1 publications · 36 citations

    1

    h-index

  3. MS
    Mechthild Schmitt‐Jansen

    Helmholtz Centre for Environmental Research, Germany

    1 publications · 39 citations

    1

    h-index

  4. KP
    Krzysztof Puszyński

    Silesian University of Technology, Poland

    1 publications · 17 citations

    1

    h-index

  5. JB
    Jan B. van Klinken

    Leiden University Medical Center, Netherlands

    1 publications · 54 citations

    1

    h-index

1–5 of 57

Institutions

42

  1. University of Rostock

    Rostock, Germany

    2 h-index

    2 publications

    306 citations

  2. University of California, San Francisco

    San Francisco, United States

    1 h-index

    5 publications

    135 citations

  3. Forschungszentrum Jülich

    Jülich, Germany

    1 h-index

    2 publications

    266 citations

  4. Leiden University Medical Center

    Leiden, The Netherlands

    1 h-index

    5 publications

    270 citations

  5. University of Leeds

    Leeds, United Kingdom

    1 h-index

    1 publications

    52 citations

  6. Erasmus MC

    Rotterdam, The Netherlands

    1 h-index

    5 publications

    270 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    2 publications

    78 citations

  8. University of Leicester

    Leicester, United Kingdom

    1 h-index

    1 publications

    54 citations

1–8 of 42

Venues

  1. EPJ Nonlinear Biomedical Physics

    1 publications · 16 citations

    1

    h-index

  2. Journal of Hazardous Materials

    1 publications · 39 citations

    1

    h-index

  3. European Journal of Biochemistry

    EJB · 1 publications · 52 citations

    1

    h-index

  4. Journal of Process Control

    1 publications · 133 citations

    1

    h-index

  5. ChemRxiv

    Repository · 1 publications · 10 citations

    1

    h-index

1–5