Concepedia

Pathway Refactoring

Pathway Refactoring is the systematic reorganization and optimization of biosynthetic pathways in combinatorial biosynthesis through the precise redesign of genetic and enzymatic components to improve metabolic flux, yield, or product diversity while maintaining or decoupling regulatory dependencies.

14

Publications

766

Citations

68

Authors

26

Institutions

Publications per year

2017–2026

12

Parents

Publications

14

Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold

Zengyi Shao, Guodong Rao, Chun Guang Li et al. · ACS Synthetic Biology · 2013 · 232 citations

, , +16

Direct Pathway Cloning Combined with Sequence- and Ligation-Independent Cloning for Fast Biosynthetic Gene Cluster Refactoring and Heterologous Expression

Paul M. D’Agostino, Tobias A. M. Gulder · ACS Synthetic Biology · 2018 · 81 citations · Full text

, , +15

CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus

Mengwan Li, Xuye Lang, Marcos Moran Cabrera et al. · Biotechnology for Biofuels · 2021 · 74 citations · Full text

, , +17

Secondary metabolites overproduction through transcriptional gene cluster refactoring

Liliya Horbal, Filipe Marques, Suvd Nadmid et al. · Metabolic Engineering · 2018 · 67 citations

, , +14

Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters

Dimitris Kallifidas, Guangde Jiang, Yousong Ding et al. · Microbial Cell Factories · 2018 · 54 citations · Full text

, , +17

1–5 of 14

Authors

68

  1. HZ
    Huimin Zhao

    University of Illinois Urbana-Champaign, United States

    4 publications · 357 citations

    4

    h-index

  2. HR
    Hengqian Ren

    University of Illinois Urbana-Champaign, United States

    2 publications · 93 citations

    2

    h-index

  3. MZ
    Meng‐Qian Zhang

    Nanjing Normal University, China

    1 publications · 16 citations

    1

    h-index

  4. JC
    Jarod C. Kelly

    University of Michigan, United States

    1 publications · 18 citations

    1

    h-index

  5. XS
    Xiyan Sun

    Chinese Academy of Sciences, China

    1 publications · 74 citations

    1

    h-index

1–5 of 68

Institutions

26

  1. University of Illinois Urbana-Champaign

    Urbana, United States

    4 h-index

    17 publications

    1.9K citations

  2. Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)

    Guangzhou, China

    1 h-index

    2 publications

    40 citations

  3. Shandong University

    Jinan, China

    1 h-index

    6 publications

    132 citations

  4. Technical University of Munich

    Munich, Germany

    1 h-index

    2 publications

    162 citations

  5. London Biofoundry

    London, United Kingdom

    1 h-index

    1 publications

    23 citations

  6. University of California, Riverside

    Riverside, United States

    1 h-index

    6 publications

    444 citations

  7. University of Michigan

    Ann Arbor, United States

    1 h-index

    7 publications

    126 citations

  8. i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

    Porto, Portugal

    1 h-index

    2 publications

    134 citations

1–8 of 26

Venues

  1. ACS Synthetic Biology

    5 publications · 395 citations

    5

    h-index

  2. ACS Chemical Biology

    2 publications · 69 citations

    2

    h-index

  3. Microbial Cell Factories

    2 publications · 77 citations

    2

    h-index

  4. Biotechnology for Biofuels

    1 publications · 74 citations

    1

    h-index

  5. The International Journal of Life Cycle Assessment

    LCA · 1 publications · 18 citations

    1

    h-index

1–5