Concepedia

Oxime Antidotes

Oxime Antidotes is a pharmacological agent that belongs to the class of chemical reactivators of inhibited acetylcholinesterase, distinguished by its ability to selectively cleave organophosphate moieties from the enzyme's active site through nucleophilic attack mediated by the oxime functional group.

152

Publications

5.2K

Citations

428

Authors

125

Institutions

Publications per year

2017–2026

22

Parents

Publications

152

Evaluation of antidotes for poisoning by organophosphorus pesticides

Martin Johnson, Dag Jacobsen, T. J. Meredith et al. · Emergency Medicine · 2000 · 209 citations

, , +16

Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning

Franz Worek, M. Bäcker, Horst Thiermann et al. · Human & Experimental Toxicology · 1997 · 159 citations

, , +17

Toxicology and pharmacology of bispyridinium oximes insight into the mechanism of action vs Soman poisoning in vivo

J CLEMENT · Fundamental and Applied Toxicology · 1981 · 147 citations

, , +10

Amidine−Oximes: Reactivators for Organophosphate Exposure

Jarosław Kalisiak, Erik C. Ralph, Jun Zhang et al. · Journal of Medicinal Chemistry · 2011 · 98 citations · Full text

, , +17

HI-6 in Man: Efficacy of the Oxime in Poisoning by Organophosphorus Insecticides

R Kuśić, Dušan Jovanović, S Randjelović et al. · Human & Experimental Toxicology · 1991 · 98 citations

, , +17

1–5 of 152

Authors

428

  1. KK
    Kamil Kuča

    University of Hradec Králové, Czechia

    33 publications · 1K citations

    21

    h-index

  2. DJ
    Daniel Jun

    University of Defence, Czechia

    16 publications · 474 citations

    14

    h-index

  3. KM
    Kamil Musílek

    University of Defence, Czechia

    12 publications · 424 citations

    12

    h-index

  4. ZK
    Zrinka Kovarik

    Institute for Medical Research and Occupational Health, Croatia

    11 publications · 402 citations

    10

    h-index

  5. MK
    Maja Katalinić

    Institute for Medical Research and Occupational Health, Croatia

    8 publications · 265 citations

    8

    h-index

1–5 of 428

Institutions

125

  1. University of Defence

    Brno, Czechia

    19 h-index

    93 publications

    2.7K citations

  2. United States Army

    Arlington, United States

    11 h-index

    42 publications

    1.6K citations

  3. Institute for Medical Research and Occupational Health

    Zagreb, Croatia

    11 h-index

    68 publications

    2.4K citations

  4. University of Hradec Králové

    Hradec Králové, Czechia

    9 h-index

    19 publications

    326 citations

  5. Charles University

    Prague, Czechia

    9 h-index

    11 publications

    292 citations

  6. Military Institute of Engineering

    Rio de Janeiro, Brazil

    7 h-index

    16 publications

    342 citations

  7. University Hospital Hradec Králové

    Hradec Králové, Czechia

    6 h-index

    17 publications

    375 citations

  8. DEVCOM Army Research Laboratory

    Adelphi, United States

    6 h-index

    14 publications

    440 citations

1–8 of 125

Venues

  1. Toxicology and Applied Pharmacology

    TAAP · 9 publications · 424 citations

    9

    h-index

  2. PubMed

    Repository · 8 publications · 163 citations

    8

    h-index

  3. Journal of Applied Toxicology

    6 publications · 171 citations

    6

    h-index

  4. 6

    h-index

  5. Drug and Chemical Toxicology

    5 publications · 106 citations

    5

    h-index

1–5