Concepedia

Otx2 Patterning

Otx2 Patterning is a developmental genetic mechanism defined by the spatially and temporally regulated expression of the Otx2 gene, which orchestrates regional identity specification in the anterior neural plate during early brain regionalization.

93

Publications

9.6K

Citations

315

Authors

129

Institutions

Publications per year

2017–2026

6

Parents

Publications

93

Forebrain and midbrain regions are deleted in <i>Otx2</i>−/− mutants due to a defective anterior neuroectoderm specification during gastrulation

Dario Acampora, Sylvie Mazan, Yvan Lallemand et al. · Development · 1995 · 708 citations

, , +14

Mouse Otx2 functions in the formation and patterning of rostral head.

Isao Matsuo, Shigeru Kuratani, C. Kimura et al. · Genes & Development · 1995 · 696 citations · Full text

, , +17

A targeted mouse <i>Otx2</i> mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain

Siew-Lan Ang, Ou Jin, Muriel Rhinn et al. · Development · 1996 · 507 citations

, , +17

Experience-Dependent Transfer of Otx2 Homeoprotein into the Visual Cortex Activates Postnatal Plasticity

Sayaka Sugiyama, Ariel A. Di Nardo, Shinichi Aizawa et al. · Cell · 2008 · 497 citations · Full text

, , +16

The <i>Xenopus</i> homologue of <i>Otx2</i> is a maternal homeobox gene that demarcates and specifies anterior body regions

Maria Pannese, Cristiana Polo, Massimiliano Andreazzoli et al. · Development · 1995 · 428 citations

, , +17

1–5 of 93

Authors

315

  1. AS
    Antonio Simeone

    Institute of Genetics and Biophysics, Italy

    15 publications · 2.1K citations

    15

    h-index

  2. SA
    Shinichi Aizawa

    Kumamoto University, Japan

    14 publications · 1.9K citations

    14

    h-index

  3. DA
    Dario Acampora

    Institute of Genetics and Biophysics, Italy

    11 publications · 1.6K citations

    11

    h-index

  4. IM
    Isao Matsuo

    Kumamoto University, Japan

    8 publications · 1.7K citations

    8

    h-index

  5. DK
    Daisuke Kurokawa

    The University of Tokyo, Japan

    7 publications · 350 citations

    7

    h-index

1–5 of 315

Institutions

129

  1. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    48 publications

    9.7K citations

  2. Inserm

    Paris, France

    15 h-index

    49 publications

    5.7K citations

  3. Institute of Genetics and Biophysics

    Naples, Italy

    14 h-index

    37 publications

    8.1K citations

  4. King's College London

    London, United Kingdom

    10 h-index

    42 publications

    3.6K citations

  5. Kumamoto University

    Kumamoto, Japan

    6 h-index

    26 publications

    5K citations

  6. RIKEN Center for Computational Science

    Kobe, Japan

    5 h-index

    7 publications

    265 citations

  7. Genetic Resources Center

    Tsukuba, Japan

    5 h-index

    10 publications

    579 citations

  8. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    4 h-index

    13 publications

    3.3K citations

1–8 of 129

Venues

  1. Development

    29 publications · 4.9K citations

    28

    h-index

  2. Mechanisms of Development

    MOD · 12 publications · 927 citations

    12

    h-index

  3. Developmental Biology

    10 publications · 518 citations

    10

    h-index

  4. Journal of Neuroscience

    4 publications · 277 citations

    4

    h-index

  5. 3

    h-index

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