Concepedia

Origin Licensing Control

Origin Licensing Control is a regulatory mechanism in eukaryotic DNA replication that ensures the precise assembly of pre-replication complexes at replication origins during the G1 phase, thereby restricting origin firing to a single round per cell cycle.

33

Publications

2.3K

Citations

159

Authors

76

Institutions

Publications per year

2017–2026

15

Parents

Publications

33

CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis

Niels Mailand, John F.X. Diffley · Cell · 2005 · 338 citations · Full text

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The Yeast CDK Inhibitor Sic1 Prevents Genomic Instability by Promoting Replication Origin Licensing in Late G1

Armelle Lengronne, Étienne Schwob · Molecular Cell · 2002 · 243 citations · Full text

, , +12

ATPase-dependent quality control of DNA replication origin licensing

Jordi Frigola, Dirk Remus, Amina Mehanna et al. · Nature · 2013 · 234 citations

, , +13

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Shin‐ichiro Hiraga, Tony Ly, Javier Garzón et al. · EMBO Reports · 2017 · 153 citations · Full text

, , +12

Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA

Julien Gros, Charanya Kumar, Gerard Lynch et al. · Molecular Cell · 2015 · 139 citations · Full text

, , +14

1–5 of 33

Authors

159

  1. SP
    Stephen P. Bell

    Massachusetts Institute of Technology, United States

    5 publications · 205 citations

    5

    h-index

  2. LJ
    Larry J. Friedman

    Brandeis University, United States

    3 publications · 144 citations

    3

    h-index

  3. JG
    Jeff Gelles

    Brandeis University, United States

    3 publications · 144 citations

    3

    h-index

  4. DR
    Dirk Remus

    Memorial Sloan Kettering Cancer Center, United States

    3 publications · 403 citations

    3

    h-index

  5. JG
    Jeanette Gowen Cook

    University of North Carolina at Chapel Hill, United States

    3 publications · 110 citations

    3

    h-index

1–5 of 159

Institutions

76

  1. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    15 publications

    596 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    12 publications

    536 citations

  3. Brandeis University

    Waltham, United States

    4 h-index

    7 publications

    309 citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    12 publications

    554 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    19 publications

    764 citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    9 publications

    1.1K citations

  7. Institut de Génétique Humaine

    Montpellier, France

    2 h-index

    3 publications

    291 citations

  8. Cornell University

    Ithaca, United States

    2 h-index

    3 publications

    209 citations

1–8 of 76

Venues

  1. Nature Communications

    3 publications · 154 citations

    3

    h-index

  2. Molecular Cell

    3 publications · 417 citations

    3

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 85 citations

    3

    h-index

  4. Nucleic Acids Research

    3 publications · 194 citations

    3

    h-index

  5. Cell

    2 publications · 388 citations

    2

    h-index

1–5