Concepedia

Organ Uptake

Organ Uptake is a pharmacokinetic process that refers to the absorption and accumulation of a drug by a specific organ or tissue from the systemic circulation, distinguished by its dependence on blood flow, tissue permeability, and molecular characteristics of the drug.

404

Publications

19.5K

Citations

1.7K

Authors

492

Institutions

Publications per year

2017–2026

42

Parents

Publications

404

Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

WH Oldendorf · American Journal of Physiology-Legacy Content · 1971 · 1.7K citations

, , +9

DOPAMINE IN THE MESOLIMBIC SYSTEM OF THE RAT BRAIN: ENDOGENOUS LEVELS AND THE EFFECTS OF DRUGS ON THE UPTAKE MECHANISM AND STIMULATION OF ADENYLATE CYCLASE ACTIVITY

A. S. Horn, A. Claudio Cuello, R. J. Miller · Journal of Neurochemistry · 1974 · 341 citations

, , +17

Altered Metabolism (In Vivo and In Vitro) of Plasma Lipoproteins after Selective Chemical Modification of Lysine Residues of the Apoproteins

Robert W. Mahley, Thomas L. Innerarity, Karl H. Weisgraber et al. · Journal of Clinical Investigation · 1979 · 316 citations · Full text

, , +12

Comparison of cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated gadolinium nanoparticles in tumor-bearing mice

Moses O. Oyewumi, Robert A. Yokel, Michael Jay et al. · Journal of Controlled Release · 2004 · 292 citations

, , +17

THE UPTAKE OF NORADRENALINE BY THE ISOLATED PERFUSED RAT HEART

Leslie L. Iversen · British Journal of Pharmacology and Chemotherapy · 1963 · 284 citations · Full text

, , +9

1–5 of 404

Authors

1.7K

  1. WM
    William M. Pardridge

    University of California, Los Angeles, United States

    9 publications · 425 citations

    9

    h-index

  2. YS
    Yuichi Sugiyama

    The University of Tokyo, Japan

    5 publications · 295 citations

    5

    h-index

  3. SP
    Steven P. Rowe

    Johns Hopkins University, United States

    5 publications · 151 citations

    5

    h-index

  4. MG
    Martin G. Pomper

    Johns Hopkins University, United States

    5 publications · 146 citations

    5

    h-index

  5. MM
    Mart Mannik

    University of Washington, United States

    4 publications · 167 citations

    4

    h-index

1–5 of 1.7K

Institutions

492

  1. Johns Hopkins University

    Baltimore, United States

    9 h-index

    45 publications

    1.5K citations

  2. National Institutes of Health

    Bethesda, United States

    6 h-index

    16 publications

    1.8K citations

  3. University of California, Irvine

    Irvine, United States

    6 h-index

    14 publications

    342 citations

  4. Lund University

    Lund, Sweden

    5 h-index

    17 publications

    467 citations

  5. Inserm

    Paris, France

    5 h-index

    16 publications

    587 citations

  6. Uppsala University

    Uppsala, Sweden

    5 h-index

    19 publications

    722 citations

  7. Johns Hopkins Medicine

    Baltimore, United States

    5 h-index

    20 publications

    596 citations

  8. The University of Tokyo

    Tokyo, Japan

    5 h-index

    16 publications

    596 citations

1–8 of 492

Venues

  1. PubMed

    Repository · 52 publications · 2.3K citations

    28

    h-index

  2. 13

    h-index

  3. Journal of Nuclear Medicine

    9 publications · 466 citations

    9

    h-index

  4. 8

    h-index

  5. American Journal of Physiology-Legacy Content

    8 publications · 1.9K citations

    8

    h-index

1–5