Concepedia

Opsin Engineering

Opsin Engineering is a methodological framework in optogenetics that involves the rational design and modification of light-sensitive opsin proteins to impart novel functional properties, such as altered spectral sensitivity, kinetics, or ion selectivity, thereby enabling precise spatiotemporal control of cellular activity in targeted biological systems.

27

Publications

2K

Citations

213

Authors

78

Institutions

Publications per year

2017–2026

14

Parents

Publications

27

The Microbial Opsin Family of Optogenetic Tools

Feng Zhang, Johannes Vierock, Ofer Yizhar et al. · Cell · 2011 · 518 citations · Full text

, , +9

Photocatalytic <i>E</i> → <i>Z</i> Isomerization of Polarized Alkenes Inspired by the Visual Cycle: Mechanistic Dichotomy and Origin of Selectivity

Jan B. Metternich, Denis G. Artiukhin, Mareike C. Holland et al. · The Journal of Organic Chemistry · 2017 · 161 citations · Full text

, , +14

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

Xin Gong, Diego Mendoza-Halliday, Jonathan T. Ting et al. · Neuron · 2020 · 160 citations · Full text

, , +13

Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation

Ken Berglund, Kara Clissold, Haofang E. Li et al. · Proceedings of the National Academy of Sciences · 2016 · 121 citations · Full text

, , +14

Atomistic design of microbial opsin-based blue-shifted optogenetics tools

Hideaki Kato, Motoshi Kamiya, Seiya Sugo et al. · Nature Communications · 2015 · 109 citations · Full text

, , +15

1–5 of 27

Authors

213

  1. UH
    Ute Hochgeschwender

    Central Michigan University, United States

    3 publications · 221 citations

    3

    h-index

  2. KB
    Ken Berglund

    Emory University, United States

    3 publications · 172 citations

    3

    h-index

  3. RE
    Robert E. Gross

    Emory University, United States

    3 publications · 125 citations

    3

    h-index

  4. KD
    Karl Deisseroth

    Stanford University, United States

    3 publications · 718 citations

    3

    h-index

  5. MG
    Marta Gajowa

    University of California, Berkeley, United States

    3 publications · 202 citations

    3

    h-index

1–5 of 213

Institutions

78

  1. Emory University

    Atlanta, United States

    4 h-index

    15 publications

    586 citations

  2. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    13 publications

    592 citations

  3. Inserm

    Paris, France

    3 h-index

    5 publications

    326 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    11 publications

    842 citations

  5. Central Michigan University

    Mount Pleasant, United States

    3 h-index

    8 publications

    531 citations

  6. University of California, Berkeley

    Berkeley, United States

    3 h-index

    27 publications

    1.6K citations

  7. Stanford University

    Stanford, United States

    2 h-index

    3 publications

    1.2K citations

  8. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    3 publications

    614 citations

1–8 of 78

Venues

  1. Neuron

    3 publications · 357 citations

    3

    h-index

  2. eLife

    3 publications · 142 citations

    3

    h-index

  3. Journal of Neuroscience Research

    JNR · 3 publications · 113 citations

    3

    h-index

  4. Nature Communications

    2 publications · 166 citations

    2

    h-index

  5. ChemPlusChem

    1 publications · 20 citations

    1

    h-index

1–5