Concepedia

Oatp-mediated Uptake

OATP-Mediated Uptake is a hepatic transport mechanism belonging to the class of solute carrier transport processes, distinguished by its specific dependence on organic anion transporting polypeptides (OATPs) for the sinusoidal membrane uptake of endogenous compounds and xenobiotics into hepatocytes during first-pass metabolism.

390

Publications

32.5K

Citations

1.7K

Authors

408

Institutions

Publications per year

2017–2026

79

Parents

Publications

390

Molecular Identification and Characterization of Novel Members of the Human Organic Anion Transporter (OATP) Family

Ikumi Tamai, Jun‐ichi Nezu, Hiroshi Uchino et al. · Biochemical and Biophysical Research Communications · 2000 · 639 citations

, , +10

Polymorphisms in OATP-C

Rommel G. Tirona, Brenda F. Leake, Gracia Merino et al. · Journal of Biological Chemistry · 2001 · 624 citations · Full text

, , +13

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

Jörg König, Yunhai Cui, Anne T. Nies et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2000 · 620 citations · Full text

, , +13

OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

Mirjana Cvetković, Brenda F. Leake, Martin F. Fromm et al. · Drug Metabolism and Disposition · 1999 · 595 citations

, , +17

Expression cloning of a rat liver Na(+)-independent organic anion transporter.

Emmanuel Jacquemin, Bruno Hagenbuch, Bruno Stieger et al. · Proceedings of the National Academy of Sciences · 1994 · 537 citations

, , +12

1–5 of 390

Authors

1.7K

  1. BS
    Bruno Stieger

    University Hospital of Zurich, Switzerland

    27 publications · 3.5K citations

    25

    h-index

  2. YS
    Yuichi Sugiyama

    The University of Tokyo, Japan

    29 publications · 3.7K citations

    24

    h-index

  3. BH
    Bruno Hagenbuch

    University Hospital of Zurich, Switzerland

    27 publications · 3.2K citations

    24

    h-index

  4. PJ
    Peter J. Meier

    University Hospital of Zurich, Switzerland

    19 publications · 3K citations

    18

    h-index

  5. KM
    Kazuya Maeda

    The University of Tokyo, Japan

    19 publications · 2.2K citations

    17

    h-index

1–5 of 1.7K

Institutions

408

  1. University Hospital of Zurich

    Zurich, Switzerland

    25 h-index

    82 publications

    13.8K citations

  2. University of Kansas Medical Center

    Kansas City, United States

    24 h-index

    99 publications

    7.6K citations

  3. The University of Tokyo

    Tokyo, Japan

    22 h-index

    68 publications

    8.3K citations

  4. Pfizer (United States)

    New York, United States

    16 h-index

    110 publications

    6.7K citations

  5. Kanazawa University

    Kanazawa, Japan

    15 h-index

    80 publications

    8.7K citations

  6. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    13 h-index

    45 publications

    3.1K citations

  7. Albert Einstein College of Medicine

    Bronx, United States

    11 h-index

    29 publications

    2.3K citations

  8. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    10 h-index

    72 publications

    4.4K citations

1–8 of 408

Venues

  1. Drug Metabolism and Disposition

    66 publications · 6.5K citations

    40

    h-index

  2. 32

    h-index

  3. Molecular Pharmaceutics

    25 publications · 1.2K citations

    20

    h-index

  4. Molecular Pharmacology

    19 publications · 1K citations

    16

    h-index

  5. Xenobiotica

    15 publications · 563 citations

    14

    h-index

1–5