Concepedia

Nucleotide Insertion At Junctions

Nucleotide Insertion At Junctions is a molecular genetic process characterized by the non-templated addition of nucleotides at the junctions between variable (V), diversity (D), and joining (J) gene segments during T-cell receptor gene rearrangement, mediated by terminal deoxynucleotidyl transferase (TdT) to increase receptor diversity.

44

Publications

3.4K

Citations

163

Authors

80

Institutions

Publications per year

2017–2026

4

Variants

N-additionN-nucleotide Addition

Parents

Publications

44

Lack of N Regions in Antigen Receptor Variable Region Genes of TdT-Deficient Lymphocytes

Toshihisa Komori, Ami Okada, Valerie Stewart et al. · Science · 1993 · 479 citations

, , +17

Neuronal pp60 <sup> c- <i>src</i> </sup> Contains a Six-Amino Acid Insertion Relative to Its Non-Neuronal Counterpart

Ricardo Martínez, Bernard Mathey-Prévôt, André Bernards et al. · Science · 1987 · 313 citations

, , +11

Design of immobile nucleic acid junctions

Nadrian C. Seeman, Neville R. Kallenbach · Biophysical Journal · 1983 · 257 citations · Full text

, , +9

The lepidopteran transposon vector, <i>piggyBac</i> , mediates germ-line transformation in the Mediterranean fruit fly

Alfred M. Handler, Susan D. McCombs, Malcolm J. Fraser et al. · Proceedings of the National Academy of Sciences · 1998 · 257 citations · Full text

, , +17

Precise and Predictable CRISPR Chromosomal Rearrangements Reveal Principles of Cas9-Mediated Nucleotide Insertion

Jia Shou, Jinhuan Li, Yingbin Liu et al. · Molecular Cell · 2018 · 218 citations · Full text

, , +10

1–5 of 44

Authors

163

  1. JH
    John H. Wilson

    Baylor College of Medicine, United States

    2 publications · 175 citations

    2

    h-index

  2. DB
    David B. Roth

    Baylor College of Medicine, United States

    2 publications · 175 citations

    2

    h-index

  3. JT
    Joseph T. Meier

    California Institute of Technology, United States

    2 publications · 102 citations

    2

    h-index

  4. PW
    Philip W. Tucker

    The University of Texas Southwestern Medical Center, United States

    2 publications · 72 citations

    2

    h-index

  5. WA
    William A. Kuziel

    The University of Texas at Austin, United States

    2 publications · 72 citations

    2

    h-index

1–5 of 163

Institutions

80

  1. Harvard University

    Cambridge, United States

    3 h-index

    11 publications

    872 citations

  2. University of Vienna

    Vienna, Austria

    2 h-index

    9 publications

    267 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    6 publications

    215 citations

  4. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    3 publications

    399 citations

  5. Washington University in St. Louis

    St Louis, United States

    2 h-index

    3 publications

    159 citations

  6. Institut Pasteur

    Paris, France

    2 h-index

    8 publications

    230 citations

  7. New York University

    New York, United States

    2 h-index

    3 publications

    176 citations

  8. Baylor College of Medicine

    Houston, United States

    2 h-index

    6 publications

    525 citations

1–8 of 80

Venues

  1. Nucleic Acids Research

    5 publications · 134 citations

    5

    h-index

  2. Molecular and Cellular Biology

    MCB · 4 publications · 277 citations

    4

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 565 citations

    3

    h-index

  4. Journal of Bacteriology

    JB · 2 publications · 53 citations

    2

    h-index

  5. Journal of Virology

    JVI · 2 publications · 95 citations

    2

    h-index

1–5