Concepedia

Nucleosome-dependent Pausing

Nucleosome-Dependent Pausing is a form of transcriptional pausing wherein RNA polymerase II is transiently halted during elongation due to physical and energetic barriers imposed by the presence of a nucleosome in its path along the DNA template.

13

Publications

1.8K

Citations

59

Authors

33

Institutions

Publications per year

2017–2026

4

Parents

Publications

13

Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation

Daniel A. Gilchrist, Gilberto dos Santos, David C. Fargo et al. · Cell · 2010 · 418 citations · Full text

, , +12

Nucleosomes Are Context-Specific, H2A.Z-Modulated Barriers to RNA Polymerase

Christopher M. Weber, Srinivas Ramachandran, Steven Henikoff · Molecular Cell · 2014 · 398 citations · Full text

, , +12

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

Michael G. Izban, Donal S. Luse · Genes & Development · 1991 · 245 citations · Full text

, , +17

A nucleosome‐dependent static loop potentiates estrogen‐regulated transcription from the Xenopus vitellogenin B1 promoter in vitro.

Christopher-Johannes Schild, Francois X. Claret, Walter Wahli et al. · The EMBO Journal · 1993 · 220 citations

, , +15

Structural insight into nucleosome transcription by RNA polymerase II with elongation factors

Haruhiko Ehara, Tomoya Kujirai, Y. Fujino et al. · Science · 2019 · 184 citations

, , +17

1–5 of 13

Authors

59

  1. SS
    Shun‐ichi Sekine

    The University of Tokyo, Japan

    3 publications · 221 citations

    3

    h-index

  2. TK
    Tomoya Kujirai

    The University of Tokyo, Japan

    3 publications · 221 citations

    3

    h-index

  3. HK
    Hitoshi Kurumizaka

    Waseda University, Japan

    3 publications · 221 citations

    3

    h-index

  4. HE
    Haruhiko Ehara

    RIKEN Center for Biosystems Dynamics Research, Japan

    3 publications · 221 citations

    3

    h-index

  5. MA
    Munetaka Akatsu

    The University of Tokyo, Japan

    2 publications · 37 citations

    2

    h-index

1–5 of 59

Institutions

33

  1. RIKEN Center for Biosystems Dynamics Research

    Kobe, Japan

    3 h-index

    13 publications

    1.1K citations

  2. The University of Tokyo

    Tokyo, Japan

    3 h-index

    20 publications

    870 citations

  3. National Institutes of Health

    Bethesda, United States

    2 h-index

    6 publications

    2.1K citations

  4. Whitehead Institute for Biomedical Research

    Cambridge, United States

    1 h-index

    1 publications

    128 citations

  5. Fred Hutch Cancer Center

    Seattle, United States

    1 h-index

    3 publications

    1.2K citations

  6. Johns Hopkins University

    Baltimore, United States

    1 h-index

    2 publications

    836 citations

  7. Wayne State University

    Detroit, United States

    1 h-index

    3 publications

    36 citations

  8. University of Washington

    Seattle, United States

    1 h-index

    1 publications

    398 citations

1–8 of 33

Venues

  1. Molecular Cell

    3 publications · 578 citations

    3

    h-index

  2. Nucleic Acids Research

    2 publications · 46 citations

    2

    h-index

  3. Journal of Biological Chemistry

    JBC · 2 publications · 57 citations

    2

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 15 citations

    1

    h-index

  5. Biopolymers

    1 publications · 12 citations

    1

    h-index

1–5