Concepedia

Nuclease-substrate Recognition

Nuclease-Substrate Recognition is a molecular recognition process in which a nuclease selectively identifies and binds to specific nucleic acid sequences or structural motifs through precise protein-DNA or protein-RNA interactions, distinguishing it from general nucleic acid binding by its dependence on substrate specificity and catalytic readiness.

150

Publications

7.7K

Citations

584

Authors

225

Institutions

Publications per year

2017–2026

23

Parents

Publications

150

High sequence specificity of micrococcal nuclease

Colin Dingwall, George P. Lomonossoff, Ronald A. Laskey · Nucleic Acids Research · 1981 · 366 citations · Full text

, , +16

Substrate Recognition and Catalysis by the Exoribonuclease RNase R

Helen A. Vincent, Murray P. Deutscher · Journal of Biological Chemistry · 2006 · 259 citations · Full text

, , +14

Substrate recognition by ADAR1 and ADAR2

Swee Kee Wong, Shuji Sato, David W. Lazinski · RNA · 2001 · 243 citations · Full text

, , +13

The interaction of plasmid DNA with polyamidoamine dendrimers: mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA

Anna U. Bielinska, Jolanta F. Kukowska‐Latallo, James R. Baker · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1997 · 223 citations

, , +13

Ribonuclease selection for ribosome profiling

Maxim V. Gerashchenko, Vadim N. Gladyshev · Nucleic Acids Research · 2016 · 166 citations · Full text

, , +14

1–5 of 150

Authors

584

  1. CA
    Carol A. Fierke

    University of Michigan, United States

    4 publications · 120 citations

    4

    h-index

  2. HT
    Hiroshi Taniuchi

    National Institutes of Health, United States

    3 publications · 153 citations

    3

    h-index

  3. MF
    Masao Fujimoto

    Nara Medical University, Japan

    2 publications · 24 citations

    2

    h-index

  4. KK
    Kipchumba Kaitany

    University of Michigan, United States

    2 publications · 54 citations

    2

    h-index

  5. SA
    Sherif Abou Elela

    Université de Sherbrooke, Canada

    2 publications · 79 citations

    2

    h-index

1–5 of 584

Institutions

225

  1. National Institutes of Health

    Bethesda, United States

    9 h-index

    38 publications

    3.4K citations

  2. University of Michigan

    Ann Arbor, United States

    6 h-index

    20 publications

    1.1K citations

  3. University of California, Irvine

    Irvine, United States

    5 h-index

    13 publications

    653 citations

  4. National Institute of Arthritis and Musculoskeletal and Skin Diseases

    Bethesda, United States

    4 h-index

    12 publications

    416 citations

  5. University of California, Berkeley

    Berkeley, United States

    4 h-index

    10 publications

    594 citations

  6. Goethe University Frankfurt

    Frankfurt am Main, Germany

    3 h-index

    9 publications

    274 citations

  7. Yale University

    New Haven, United States

    3 h-index

    7 publications

    368 citations

  8. Johns Hopkins University

    Baltimore, United States

    3 h-index

    5 publications

    90 citations

1–8 of 225

Venues

  1. Nucleic Acids Research

    27 publications · 1.6K citations

    22

    h-index

  2. Journal of Biological Chemistry

    JBC · 18 publications · 1.4K citations

    17

    h-index

  3. Journal of Molecular Biology

    JMB · 8 publications · 373 citations

    8

    h-index

  4. RNA

    7 publications · 530 citations

    7

    h-index

  5. Biochemistry

    6 publications · 225 citations

    6

    h-index

1–5