Concepedia

Norbornene Ligation

Norbornene Ligation is a bioorthogonal chemical reaction that belongs to the class of inverse electron-demand Diels–Alder reactions, in which a norbornene derivative acts as the dienophile reacting selectively and rapidly with a tetrazine to enable site-specific bioconjugation under physiological conditions.

32

Publications

1.1K

Citations

127

Authors

39

Institutions

Publications per year

2017–2026

4

Parents

Publications

32

Pd(0)-Catalyzed Iodoalkynation of Norbornene Scaffolds: The Remarkable Solvent Effect on Reaction Pathway

Hui Liu, Chen Chen, Limin Wang et al. · Organic Letters · 2011 · 86 citations

, , +13

Acylazetine as a Dienophile in Bioorthogonal Inverse Electron-Demand Diels–Alder Ligation

Sander B. Engelsma, Lianne I. Willems, Claudia E. van Paaschen et al. · Organic Letters · 2014 · 64 citations

, , +12

Rh-catalyzed π-facial selective intermolecular hydroacylation of norbornenes

Keitaro Tanaka, Masakazu Tanaka, Hiroshi Suemune · Tetrahedron Letters · 2005 · 58 citations

, , +5

Stereochemistry of the insertion reaction of norbornene into a nickelallyl and a palladiumallyl bond

M.C. Gallazzi, Thomas L. Hanlon, Giovanni Vitulli et al. · Journal of Organometallic Chemistry · 1971 · 57 citations

, , +8

Synthesis, characterization, and norbornene polymerization of η3-benzylnickel(II) complexes of N-heterocyclic carbenes

S. Sujith, Eun Kyung Noh, Bun Yeoul Lee et al. · Journal of Organometallic Chemistry · 2008 · 50 citations

, , +12

1–5 of 32

Authors

127

  1. XS
    Xiaochao Shi

    Shanghai University, China

    2 publications · 65 citations

    2

    h-index

  2. MG
    M.C. Gallazzi

    Politecnico di Milano, Italy

    2 publications · 101 citations

    2

    h-index

  3. GJ
    Guo‐Xin Jin

    Fudan University, China

    2 publications · 67 citations

    2

    h-index

  4. HS
    Herman S. Overkleeft

    Leiden University, Netherlands

    2 publications · 84 citations

    2

    h-index

  5. LP
    Lido Porri

    Politecnico di Milano, Italy

    2 publications · 101 citations

    2

    h-index

1–5 of 127

Institutions

39

  1. Fudan University

    Shanghai, China

    2 h-index

    4 publications

    134 citations

  2. Leiden University

    Leiden, The Netherlands

    2 h-index

    10 publications

    508 citations

  3. University of Pisa

    Pisa, Italy

    2 h-index

    7 publications

    360 citations

  4. Collaborative Innovation Center of Chemical Science and Engineering Tianjin

    Tianjin, China

    2 h-index

    5 publications

    161 citations

  5. Politecnico di Milano

    Milan, Italy

    2 h-index

    7 publications

    360 citations

  6. Industriale Chimica (Italy)

    Saronno, Italy

    2 h-index

    7 publications

    360 citations

  7. Hebei University of Technology

    Tianjin, China

    1 h-index

    2 publications

    58 citations

  8. University of Münster

    Münster, Germany

    1 h-index

    5 publications

    220 citations

1–8 of 39

Venues

  1. Journal of Organometallic Chemistry

    5 publications · 171 citations

    5

    h-index

  2. Organometallics

    3 publications · 103 citations

    3

    h-index

  3. Journal of Molecular Catalysis A Chemical

    3 publications · 92 citations

    3

    h-index

  4. Dalton Transactions

    2 publications · 58 citations

    2

    h-index

  5. Tetrahedron Letters

    2 publications · 91 citations

    2

    h-index

1–5