Concepedia

Nonlinear One-compartment Models

Nonlinear One-Compartment Models is a pharmacokinetic model in which the rate of drug elimination from a single compartment exhibits nonlinear dependence on drug concentration, typically due to saturation kinetics, distinguishing it from linear one-compartment models that assume first-order elimination.

34

Publications

1.6K

Citations

232

Authors

83

Institutions

Publications per year

2017–2026

10

Parents

Publications

34

Production of the Hydroxyl Radical in Indoor Air

Charles J. Weschler, Helen C. Shields · Environmental Science & Technology · 1996 · 206 citations

, , +17

Perioperative Pharmacodynamics of Acetaminophen Analgesia in Children 

Brian J. Anderson, Nicholas H. G. Holford, Gerald Woollard et al. · Anesthesiology · 1999 · 183 citations · Full text

, , +17

Population Pharmacokinetics of Fluconazole in Young Infants

Kelly C. Wade, Di Wu, David Kaufman et al. · Antimicrobial Agents and Chemotherapy · 2008 · 175 citations · Full text

, , +17

Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation.

Tai‐Lin Chen, José Luís Passos‐Coelho, D A Noe et al. · PubMed · 1995 · 103 citations

, , +14

Factors Influencing Pharmacokinetics of Prophylactic Posaconazole in Patients Undergoing Allogeneic Stem Cell Transplantation

V. Kohl, Carsten Müller, Oliver A. Cornely et al. · Antimicrobial Agents and Chemotherapy · 2009 · 77 citations · Full text

, , +15

1–5 of 34

Authors

232

  1. LB
    L B Grochow

    Johns Hopkins University, United States

    2 publications · 171 citations

    2

    h-index

  2. OM
    O. Michael Colvin

    Johns Hopkins University, United States

    2 publications · 171 citations

    2

    h-index

  3. AD
    Alfonso Domínguez‐Gil

    Universidad de Salamanca, Spain

    2 publications · 98 citations

    2

    h-index

  4. MY
    Masato Yasuhara

    Tokyo Medical and Dental University, Japan

    2 publications · 78 citations

    2

    h-index

  5. MJ
    María José García Sánchez

    Universidad de Salamanca, Spain

    2 publications · 98 citations

    2

    h-index

1–5 of 232

Institutions

83

  1. Johns Hopkins University

    Baltimore, United States

    3 h-index

    6 publications

    339 citations

  2. Kyoto University Hospital

    Kyoto, Japan

    2 h-index

    2 publications

    78 citations

  3. Johns Hopkins Hospital

    Baltimore, United States

    2 h-index

    2 publications

    171 citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    5 publications

    236 citations

  5. University of Minnesota

    Minneapolis, United States

    2 h-index

    8 publications

    228 citations

  6. University Hospital Bonn

    Bonn, Germany

    2 h-index

    3 publications

    119 citations

  7. University of California, San Francisco

    San Francisco, United States

    2 h-index

    2 publications

    92 citations

  8. Universidad de Salamanca

    Salamanca, Spain

    2 h-index

    13 publications

    634 citations

1–8 of 83

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 6 publications · 434 citations

    6

    h-index

  2. Biological and Pharmaceutical Bulletin

    3 publications · 107 citations

    3

    h-index

  3. PubMed

    Repository · 3 publications · 181 citations

    3

    h-index

  4. Anesthesiology

    2 publications · 215 citations

    2

    h-index

  5. Frontiers in Pharmacology

    2 publications · 36 citations

    2

    h-index

1–5