Concepedia

Noninferiority Testing

Noninferiority Testing is a statistical hypothesis testing framework used to determine whether a new intervention is not worse than an existing standard by more than a pre-specified margin, typically in clinical trials where demonstrating equivalence or acceptable loss of efficacy is the goal.

522

Publications

46K

Citations

4.8K

Authors

1.9K

Institutions

Publications per year

2017–2026

230

Parents

Publications

522

Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy<subtitle>A Randomized Clinical Trial</subtitle>

Alan E. Jones · JAMA · 2010 · 1K citations · Full text

, , +16

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout

William B. White, Kenneth G. Saag, Michael A. Becker et al. · New England Journal of Medicine · 2018 · 891 citations · Full text

, , +16

Randomized Phase III Study of Capecitabine Plus Oxaliplatin Compared With Fluorouracil/Folinic Acid Plus Oxaliplatin As First-Line Therapy for Metastatic Colorectal Cancer

Jim Cassidy, Stephen Clarke, Eduardo Díaz‐Rubio et al. · Journal of Clinical Oncology · 2008 · 864 citations · Full text

, , +14

Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain

Leonardo Kapural, Cong Yu, Matthew W. Doust et al. · Anesthesiology · 2015 · 829 citations · Full text

, , +11

Rosiglitazone Evaluated for Cardiovascular Outcomes — An Interim Analysis

Philip Home, Stuart Pocock, Henning Beck‐Nielsen et al. · New England Journal of Medicine · 2007 · 763 citations · Full text

, , +16

1–5 of 522

Authors

4.8K

  1. HH
    Hung Hung

    United States Food and Drug Administration, United States

    6 publications · 359 citations

    6

    h-index

  2. YT
    Yi Tsong

    Center for Drug Evaluation and Research, United States

    5 publications · 339 citations

    5

    h-index

  3. SW
    Stephan Windecker

    University Hospital of Bern, Switzerland

    5 publications · 1.2K citations

    5

    h-index

  4. JR
    Julio Rosenstock

    Dallas Diabetes Research Center, United States

    5 publications · 1.3K citations

    5

    h-index

  5. LO
    Lisette Okkels Jensen

    Odense University Hospital, Denmark

    4 publications · 258 citations

    4

    h-index

1–5 of 4.8K

Institutions

1.9K

  1. Harvard University

    Cambridge, United States

    15 h-index

    35 publications

    2.9K citations

  2. Brigham and Women's Hospital

    Boston, United States

    14 h-index

    24 publications

    3.3K citations

  3. University of Toronto

    Toronto, Canada

    13 h-index

    27 publications

    8.5K citations

  4. Johns Hopkins University

    Baltimore, United States

    13 h-index

    53 publications

    11.9K citations

  5. University of California, San Francisco

    San Francisco, United States

    11 h-index

    16 publications

    1.2K citations

  6. United States Food and Drug Administration

    Silver Spring, United States

    11 h-index

    28 publications

    1.9K citations

  7. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    48 publications

    2.2K citations

  8. Emory University

    Atlanta, United States

    10 h-index

    11 publications

    1.1K citations

1–8 of 1.9K

Venues

  1. New England Journal of Medicine

    NEJM · 22 publications · 8.2K citations

    22

    h-index

  2. Journal of Clinical Oncology

    17 publications · 3K citations

    16

    h-index

  3. JAMA

    15 publications · 5K citations

    15

    h-index

  4. Journal of Biopharmaceutical Statistics

    JBS · 18 publications · 497 citations

    13

    h-index

  5. Clinical Infectious Diseases

    CID · 13 publications · 922 citations

    12

    h-index

1–5