Concepedia

Ndc80 Complex Function

Ndc80 Complex Function is a molecular mechanism within the kinetochore machinery that mediates high-affinity microtubule binding and ensures accurate chromosome segregation during cell division by coupling dynamic microtubule attachments to the regulation of the spindle assembly checkpoint.

132

Publications

10.1K

Citations

566

Authors

170

Institutions

Publications per year

2017–2026

47

Parents

Publications

132

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

Claudio Ciferri, Sebastiano Pasqualato, Emanuela Screpanti et al. · Cell · 2008 · 556 citations · Full text

, , +13

The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

Ronnie R. Wei, Jawdat Al‐Bassam, Stephen C. Harrison · Nature Structural & Molecular Biology · 2006 · 351 citations

, , +15

Molecular organization of the Ndc80 complex, an essential kinetochore component

Ronnie R. Wei, Peter K. Sorger, Stephen C. Harrison · Proceedings of the National Academy of Sciences · 2005 · 278 citations · Full text

, , +17

Hec1 and Nuf2 Are Core Components of the Kinetochore Outer Plate Essential for Organizing Microtubule Attachment Sites

Jennifer G. DeLuca, Yimin Dong, Polla Hergert et al. · Molecular Biology of the Cell · 2004 · 260 citations · Full text

, , +17

The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity

Mark L. McCleland, Richard D. Gardner, Marko J. Kallio et al. · Genes & Development · 2003 · 256 citations · Full text

, , +17

1–5 of 132

Authors

566

  1. AD
    Arshad Desai

    Ludwig Cancer Research, United States

    10 publications · 1.3K citations

    10

    h-index

  2. CL
    Charles L. Asbury

    University of Washington, United States

    10 publications · 531 citations

    10

    h-index

  3. TN
    Trisha N. Davis

    University of Washington, United States

    8 publications · 395 citations

    8

    h-index

  4. SW
    Stefan Westermann

    Research Institute of Molecular Pathology, Austria

    7 publications · 802 citations

    7

    h-index

  5. IM
    Iain M. Cheeseman

    Whitehead Institute for Biomedical Research, United States

    7 publications · 701 citations

    7

    h-index

1–5 of 566

Institutions

170

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    16 h-index

    32 publications

    3.9K citations

  2. University of Washington

    Seattle, United States

    11 h-index

    57 publications

    2.5K citations

  3. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    9 h-index

    43 publications

    3.5K citations

  4. Harvard University

    Cambridge, United States

    9 h-index

    20 publications

    2.8K citations

  5. University of California San Diego

    San Diego, United States

    9 h-index

    30 publications

    3.2K citations

  6. Research Institute of Molecular Pathology

    Vienna, Austria

    7 h-index

    29 publications

    3.8K citations

  7. University of Duisburg-Essen

    Essen, Germany

    7 h-index

    15 publications

    681 citations

  8. European Institute of Oncology

    Milan, Italy

    7 h-index

    24 publications

    6.2K citations

1–8 of 170

Venues

  1. The Journal of Cell Biology

    JCB · 21 publications · 1.9K citations

    19

    h-index

  2. Molecular Biology of the Cell

    MBC · 12 publications · 1K citations

    11

    h-index

  3. Current Biology

    11 publications · 610 citations

    11

    h-index

  4. eLife

    11 publications · 739 citations

    11

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 863 citations

    8

    h-index

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