Concepedia

Nascent Chain Interactions

Nascent Chain Interactions is a molecular biology construct that refers to the transient, co-translationally occurring associations between a growing polypeptide chain and intracellular factors—such as chaperones, targeting machinery, or other domains of the same chain—that mediate proper protein folding, localization, and maturation during synthesis on the ribosome.

86

Publications

7.2K

Citations

404

Authors

115

Institutions

Publications per year

2017–2026

15

Parents

Publications

86

Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins

Lars Ferbitz, Timm Maier, Holger Patzelt et al. · Nature · 2004 · 416 citations · Full text

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Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases.

Steven Clarke, Joseph P. Vogel, Robert J. Deschenes et al. · Proceedings of the National Academy of Sciences · 1988 · 383 citations · Full text

, , +15

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

Thomas Becker, Shashi Bhushan, A. Jarasch et al. · Science · 2009 · 294 citations

, , +13

RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin

Matthias Gautschi, Hauke Lilie, Ursula Fünfschilling et al. · Proceedings of the National Academy of Sciences · 2001 · 234 citations · Full text

, , +15

The Yeast <i>N</i><sup>α</sup>-Acetyltransferase NatA Is Quantitatively Anchored to the Ribosome and Interacts with Nascent Polypeptides

Matthias Gautschi, Süren Just, Andrej Mun et al. · Molecular and Cellular Biology · 2003 · 226 citations · Full text

, , +11

1–5 of 86

Authors

404

  1. ED
    Elke Deuerling

    University of Konstanz, Germany

    9 publications · 986 citations

    9

    h-index

  2. BB
    Bernd Bukau

    Heidelberg University, Germany

    9 publications · 1.3K citations

    9

    h-index

  3. SR
    Sabine Rospert

    University of Freiburg, Germany

    7 publications · 955 citations

    7

    h-index

  4. AE
    Arthur E. Johnson

    Texas A&M University, United States

    6 publications · 340 citations

    6

    h-index

  5. GK
    Günter Krämer

    Heidelberg University, Germany

    5 publications · 570 citations

    5

    h-index

1–5 of 404

Institutions

115

  1. Heidelberg University

    Heidelberg, Germany

    15 h-index

    77 publications

    8.1K citations

  2. University of Freiburg

    Freiburg im Breisgau, Germany

    7 h-index

    30 publications

    1.9K citations

  3. Texas A&M University

    College Station, United States

    6 h-index

    11 publications

    648 citations

  4. University of Wisconsin–Madison

    Madison, United States

    5 h-index

    26 publications

    1.7K citations

  5. Stanford University

    Stanford, United States

    5 h-index

    12 publications

    512 citations

  6. DKFZ-ZMBH Alliance

    Heidelberg, Germany

    4 h-index

    23 publications

    3.2K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    8 publications

    482 citations

  8. Center for Integrated Protein Science Munich

    Munich, Germany

    4 h-index

    14 publications

    2.8K citations

1–8 of 115

Venues

  1. Journal of Biological Chemistry

    JBC · 22 publications · 1.4K citations

    22

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.6K citations

    11

    h-index

  3. The Journal of Cell Biology

    JCB · 9 publications · 750 citations

    9

    h-index

  4. Nature Communications

    6 publications · 393 citations

    6

    h-index

  5. Nucleic Acids Research

    3 publications · 87 citations

    3

    h-index

1–5