Concepedia

Nanodisc Engineering

Nanodisc Engineering is a methodological framework in membrane protein research that involves the design and construction of nanoscale phospholipid bilayer discs stabilized by membrane scaffold proteins or synthetic polymers to solubilize and functionally stabilize membrane proteins in a near-native environment.

78

Publications

5.3K

Citations

379

Authors

155

Institutions

Publications per year

2017–2026

48

Parents

Publications

78

Directed Self-Assembly of Monodisperse Phospholipid Bilayer Nanodiscs with Controlled Size

Ilia G. Denisov, Yelena V. Grinkova, Anne A. Lazarides et al. · Journal of the American Chemical Society · 2004 · 1.1K citations

, , +17

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Mahmoud L. Nasr, Diego Baptista, Mike Strauss et al. · Nature Methods · 2016 · 281 citations · Full text

, , +13

Functional reconstitution of β<sub>2</sub>-adrenergic receptors utilizing self-assembling Nanodisc technology

Andrew J. Leitz, Timothy H. Bayburt, Alexander N. Barnakov et al. · BioTechniques · 2006 · 202 citations · Full text

, , +17

Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers

Yelena V. Grinkova, Ilia G. Denisov, Stephen G. Sligar · Protein Engineering Design and Selection · 2010 · 189 citations · Full text

, , +17

Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs

Timothy H. Bayburt, Yelena V. Grinkova, Stephen G. Sligar · Archives of Biochemistry and Biophysics · 2006 · 174 citations

, , +8

1–5 of 78

Authors

379

  1. AR
    Ayyalusamy Ramamoorthy

    University of Michigan, United States

    7 publications · 361 citations

    7

    h-index

  2. SG
    Stephen G. Sligar

    University of Illinois Urbana-Champaign, United States

    7 publications · 1.9K citations

    7

    h-index

  3. TR
    Thirupathi Ravula

    University of Michigan, United States

    6 publications · 340 citations

    6

    h-index

  4. FB
    Frank Bernhard

    Goethe University Frankfurt, Germany

    5 publications · 195 citations

    5

    h-index

  5. GM
    Giacomo M. Di Mauro

    University of Michigan, United States

    4 publications · 219 citations

    4

    h-index

1–5 of 379

Institutions

155

  1. University of Michigan

    Ann Arbor, United States

    13 h-index

    66 publications

    3.7K citations

  2. University of Illinois Urbana-Champaign

    Urbana, United States

    7 h-index

    23 publications

    6.2K citations

  3. Goethe University Frankfurt

    Frankfurt am Main, Germany

    5 h-index

    25 publications

    1.1K citations

  4. Harvard University

    Cambridge, United States

    5 h-index

    22 publications

    3.1K citations

  5. BioSurfaces (United States)

    Ashland, United States

    4 h-index

    16 publications

    994 citations

  6. Huazhong University of Science and Technology

    Wuhan, China

    3 h-index

    5 publications

    492 citations

  7. Martin Luther University Halle-Wittenberg

    Halle, Germany

    3 h-index

    3 publications

    142 citations

  8. University of Kaiserslautern

    Kaiserslautern, Germany

    3 h-index

    20 publications

    878 citations

1–8 of 155

Venues

  1. 5

    h-index

  2. Scientific Reports

    5 publications · 204 citations

    5

    h-index

  3. Nanoscale

    4 publications · 198 citations

    4

    h-index

  4. Methods in molecular biology

    Book series · 3 publications · 49 citations

    3

    h-index

  5. Structure

    3 publications · 244 citations

    3

    h-index

1–5